Results 41 to 50 of about 7,846,955 (114)

Bortezomib-based immunosuppression after reduced-intensity conditioning hematopoietic stem cell transplantation: randomized phase II results

Haematologica, 2018
Aprior phase I/II trial of bortezomib/tacrolimus/methotrexate prophylaxis after human leukocyte antigen (HLA)-mismatched reduced intensity conditioning allogeneic hematopoietic stem cell transplantation documented low acute graft-versus-host disease ...
John Koreth, Haesook T. Kim, Paulina B. Lange, Samuel J. Poryanda, Carol G. Reynolds, Sharmila Chamling Rai, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Brett Glotzbecker, Rushdia Yusuf, Sarah Nikiforow, Yi-Bin Chen, Bimalangshu Dey, Malgorzata McMasters, Jerome Ritz, Bruce R. Blazar, Robert J. Soiffer, Joseph H. Antin, Edwin P. Alyea   +19 more
doaj   +1 more source

Ruxolitinib in steroid refractory graft-vs.-host disease: a case report

Journal of Hematology & Oncology, 2016
Background Allogeneic hematopoietic stem cell transplantation (HSCT) is potentially curative in a variety of hematological malignancies. Graft-vs.-host disease (GvHD) remains a life-threatening complication.
Enrico Maffini, Luisa Giaccone, Moreno Festuccia, Lucia Brunello, Ilaria Buondonno, Dario Ferrero, Mario Boccadoro, Chiara Dellacasa, Alessandro Busca, Domenico Novero, Benedetto Bruno   +10 more
doaj   +1 more source

The rationale behind grafting haploidentical hematopoietic stem cells

Hematology
The ability to perform hematopoietic cell transplant across major histocompatibility complex barriers can dramatically increase the availability of donors and allow more patients across the world to pursue curative transplant procedures for underlying ...
Richard T. Maziarz, Rachel J. Cook
doaj   +1 more source

Cutaneous graft-versus-host disease after hematopoietic stem cell transplant - a review [PDF]

, 2016
Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplants (allo-HSCT) associated with significant morbidity and mortality. The earliest and most common manifestation is cutaneous graft-versus-host disease.
Pérez,Jose Carlos Jaime, Alanis,Julio Cesar Salas, Pérez, Jose Carlos Jaime, Candiani, Jorge Ocampo, Candiani,Jorge Ocampo, Villarreal Villarreal, César Daniel, Alanis, Julio Cesar Salas, Villarreal,Cesar Daniel Villarreal, Ocampo Candiani, Jorge, Salas Alanís, Julio César, Jaime Pérez, José Carlos   +10 more
core   +1 more source

Novel regulatory therapies for prevention of Graft-versus-host disease [PDF]

, 2012
Graft-versus-host disease is one of the major transplant-related complications in allogeneic hematopoietic stem cell transplantation. Continued efforts have been made to prevent the occurrence of severe graft-versus-host disease by eliminating or ...
Joseph Leventhal, Suzanne T Ildstad, Leventhal, Joseph, Xu Hong, Yiming Huang, Goode Idona, Hong Xu, Idona Goode, Ildstad Suzanne T, Huang Yiming, Leventhal Joseph   +10 more
core   +2 more sources

Comparison of the Efficacy of Topical Triamcinolone in Orabase and Curcumin in Orabase in Oral Graft-versus-Host Disease

Frontiers in Dentistry, 2017
Objectives: Graft-versus-host disease (GVHD) is among the most frequent complications of allogeneic hematopoietic stem cell transplantation (HSCT). GVHD has several clinical manifestations in the oral cavity, including painful desquamative erythema ...
Arash Mansourian, Babak Bahar, Mahdieh Sadat Moosavi, Massoud Amanlou, Shahabodin Babaeifard   +4 more
doaj  

CD4+FOXP3+ Regulatory T Cell Therapies in HLA Haploidentical Hematopoietic Transplantation

Frontiers in Immunology, 2019
Since their discovery CD4+FOXP3+ regulatory T cells (Tregs) represented a promising tool to induce tolerance in allogeneic hematopoietic cell transplantation.
Antonella Mancusi, Sara Piccinelli, Andrea Velardi, Antonio Pierini   +3 more
doaj   +1 more source

Akut Graft versus Host Hastalığı

, 2019
Akut Graft vs. Host Hastalığı (GVHH); donör immun hücrelerin, konak (host) dokular üzerinde yarattığı reaksiyondur. Süreç; donörün aktive T hücrelerinin, inflamatuar bir kaskad ile konak epitelyal hücrelerine zarar vermesiyle oluşmaktadır.
Erkman Sanrı
core   +1 more source

Immunoregulatory CD4-CD8- T cells as a potential therapeutic tool for transplantation, autoimmunity and cancer

Frontiers in Immunology, 2013
A central objective in organ transplantation and the treatment or prevention of autoimmune disease is the achievement of antigen-specific immune tolerance.
Erin E Hillhouse, Jean-Sébastien eDelisle, Sylvie eLesage   +2 more
doaj   +1 more source

MiR-146a and miR-155 Expression Levels in Acute Graft-Versus-Host Disease Incidence

Frontiers in Immunology, 2016
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is a curative treatment for numerous haematological malignancies. However, acute graft-versus-host disease (aGVHD) is still the major complication causing mortality.
Sadaf eAtarod, Mohammed Mahid Ahmed, Clare eLendrem, Kim Frances Pearce, Wei eCope, Jean eNorden, Xiao-Nong eWang, Matthew eCollin, Anne Mary Dickinson   +8 more
doaj   +1 more source