Results 61 to 70 of about 7,846,955 (114)

Ocular Graft versus Host Disease

, 2015
Allogeneic hematopoietic stem cell transplantation is considered the standard of care for hematological and lymphoid malignancies. One of the complications associated to this therapy is an immune-mediated reaction known as graft versus host disease with ...
Paulo E.C. Dantas
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Management of Ocular Graft-Versus-Host Disease: A Brief Review [PDF]

, 2019
Graft-versus-host disease (GVHD) remains a major complication following hematopoietic stem cell transplantation (HSCT). Ocular GVHD develops in a substantial number of patients following HSCT and 60 % to 90 % of patients with systemic GVHD experience the
Soleimani, Mohammad, Samadi , Melika
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Suicide gene therapy for graft-versus-host disease

, 2010
In allogeneic hematopoietic stem cell transplantation, donor-derived T cells are key players for early immune reconstitution and efficient engraftment, as well as the graft-versus-leukemia and graft-versus-infection effects.
Evren Alici, Anna-Maria Georgoudaki, Alici, E,, Georgoudaki, A-M, Sutlu, T,, Tolga Sutlu   +5 more
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Toll-Like Receptor Stimulation by MicroRNAs in Acute Graft-vs.-Host Disease

Frontiers in Immunology, 2018
Acute graft-vs.-host disease (aGVHD) is a frequent complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), accounting for substantial morbidity and mortality associated with this treatment modality.
Nina C. Zitzer, Nina C. Zitzer, Ramiro Garzon, Parvathi Ranganathan   +3 more
doaj   +1 more source

Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells

, 1999
Graft versus host disease, an alloimmune attack on host tissues mounted by donor T cells, is the most important toxicity of allogeneic bone marrow transplantation. The mechanism by which allogeneic T cells are initially stimulated is unknown. In a murine
Matthew S. Couzens, Jennifer McNiff, Stephen G. Emerson, Jinli Liu, Cheng Bi Tang, Mark J. Shlomchik, Warren D. Shlomchik, Marie E. Robert   +7 more
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The IL-12 Cytokine and Receptor Family in Graft-vs.-Host Disease

Frontiers in Immunology, 2019
Allogeneic hematopoietic cell transplantation (allo-HCT) is performed with curative intent for high- risk blood cancers and bone marrow failure syndromes; yet the development of acute and chronic graft-vs.-host disease (GVHD) remain preeminent causes of ...
David Bastian, Yongxia Wu, Brian C. Betts, Xue-Zhong Yu, Xue-Zhong Yu   +4 more
doaj   +1 more source

Impact of cytokine gene polymorphisms on graft-vs-host disease

, 2008
Allogeneic hematopoietic stem cell transplantation (SCT) remains the only available curative therapy for hematological malignancy. It does, however, result in significant morbidity and mortality, predominantly as a consequence of infections, leukemic ...
Markey, K. A., MacDonald, K. P. A., Hill, G. R.   +2 more
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Combination of pleuroparenchymal fibroelastosis with non-specific interstitial pneumonia and bronchiolitis obliterans as a complication of hematopoietic stem cell transplantation — Clues to a potential mechanism [PDF]

, 2019
Pleuroparenchymal fibroelastosis (PPFE) is a newly described entity of interstitial lung disease,which has been recently recognized as a rare complication of bone marrow transplantation.
Bychkov, Andrey, Kadota, Jun-ichi, Mari Yamasue, Junya Fukuoka, Fukuoka, Junya, Yoshiaki Zaizen, Oo, Zun Pwint, Zaizen, Yoshiaki, Yamasue, Mari, Zun Pwint Oo, Andrey Bychkov, Jun-ichi Kadota   +11 more
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Cytokine Detection and Modulation in Acute Graft vs. Host Disease in Mice

Mediators of Inflammation, 1994
A murine model for acute lethal graft vs. host disease (GVHD) was used to study the role that a number of cytokines play in the development of lethal GVHD. In this study we focused on the role of IL-1, IL-2, IL-4, IL-6, IFN-γ and TNF-α.
A. C. Knulst, G. J. M. Tibbe, C. Bril-Bazuin, E. G. Breedland, A. van Oudenaren, R. Benner, H. F. J. Savelkoul   +6 more
doaj   +1 more source

Phenotypical diversity of airway morphology in chronic lung graft vs. host disease after stem cell transplantation

, 2019
Pulmonary graft vs. host disease is a diverse and underestimated complication following allogenic hematopoietic stem cell transplantation. We aimed to compare the airway architecture with chronic lung allograft dysfunction post lung transplantation ...
Dubbeldam, Adriana, Schoemans, Helene, Vanaudenaerde, Bart B.M., Boone, Matthieu N., van Raemdonck, Dirk ML, Van Raemdonck, Dirk, McDonough, John E, Vanaudenaerde, Bart M, Boone, Matthieu M.N., Verleden, Stijn E., Verleden, Stijn E, Schoemans, Helene HM, Verschakelen, Johny, Van Hoorebeke, Luc, McDonough, John E., Weynand, Birgit, Vanaudenaerde, Bart M., Verleden, Geert, Verleden, Geert M, Knoop, Christiane, Boone, Matthieu, Vos, Robin, Verleden, Geert M., Verbeken, Erik   +23 more
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