Results 71 to 80 of about 7,846,955 (114)
The Role of Co-stimulatory/Co-inhibitory Signals in Graft-vs.-Host Disease [PDF]
, 2018 Allogeneic hematopoietic cell transplantation (allo-HCT) is an effective immunotherapeutic approach for various hematologic and immunologic ailments. Despite the beneficial impact of allo-HCT, its adverse effects cause severe health concerns.
Sandeep Kumar +2 more
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Human Mesenchymal Stem Cell Therapy for Acute Graft Versus Host Disease [PDF]
, 2016 Acute graft versus host disease (GVHD) is the most critical complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The understanding of major histocompatibility complex (MHC) and the development of acute GVHD prophylaxis have ...
Miura, Yasuo, Yoshioka, Satoshi
core +1 more source
Complement and CD4+ T cells drive context-specific corneal sensory neuropathy
eLife, 2019 Whether complement dysregulation directly contributes to the pathogenesis of peripheral nervous system diseases, including sensory neuropathies, is unclear.
Derek J Royer +7 more
doaj +1 more source
Hematology, Transfusion and Cell TherapyIntroduction: Donor age and relationship has emerged as a key modifiable variable in haploidentical hematopoietic cell transplantation, with younger and sibling donors associated with reduced non-relapse mortality and graft-versus-host disease in adult ...
Luiza Dornelles Penteado PACHECO E SILVA +23 more
doaj +1 more source
Manipulating the Immunologic Characteristics of Both Graft and Host to Improve Transplant Outcome
, 1998 Background Several critical outcomes of allogeneic stem cell transplantation for hematologic malignancies such as engraftment, incidence of graft-vs-host disease (GVHD) and disease-free survival depend on a balance between residual host and infused donor
Stephen J. Noga, Paul V. O'donnell
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Characterization of a subpopulation in neonatal thymus which suppresses the graft-vs.-host reaction
, 1983 Thymus cells from neonatal and infant mice were found to have a high capacity to prevent mortality from acute graft-vs-host disease as compared with spleen cells from stable radiation chimeras.
Knaan Shanzer, S., Bekkum, D.W. van
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Immunologic tolerance to skin allograft after graft-versus-host disease.
, 2007 We report the observation of a young girl suffering from acute myeloid luekemia who developed chronic graft-versus-host disease with major skin involvement after a bone marrow graft from her histocompatible brother. She developed an immunologic tolerance
VanWijck, Romain R +9 more
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International Chronic Ocular Graft-vs-Host-Disease (GVHD) Consensus Group: Proposed Diagnostic Criteria for Chronic GVHD (Part I) [PDF]
, 2013 The International Chronic Ocular GVHD Consensus Group held 4 working meetings to define new diagnostic metrics for chronic ocular graft-versus-host disease (GVHD).
Reza Dana (4497826) +9 more
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, 2019 The immune-mediated tissue destruction of graft-vs-host disease (GvHD) remains a major barrier to greater use of hematopoietic stem cell transplantation (HSCT).
E. Ilker Ozay +13 more
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Eczematoid graft-vs-host disease
, 2007 Background: Chronic cutaneous graft-vs-host disease (GVHD) is generally classified by whether lesions have a lichenoid or sclerodermatous morphology. Other unusual clinical forms have been reported that exhibit the features of dermatomyositis and lupus ...
Du Vivier, A W P +9 more
core +1 more source