Results 31 to 40 of about 7,846,955 (114)

Efficacy of Triple Prophylaxis for Prevention of Graft-Versus-Host Disease in Matched Sibling Allogeneic Peripheral Blood Hematopoietic Stem Cell Transplantation in Pediatric Patients

International Journal of Medical Students, 2023
BACKGROUND: Graft-versus-host disease (GVHD) continues to compromise the overall success of allogenic hematopoietic stem cell transplantation. It is the most important cause of morbidity and non-relapse mortality after allogeneic hematopoietic stem cell
Fernando Tienda-López, Mariana Díaz-Ruiz, Jorge Marcos-García, Óscar González-Llano, Valentine Jiménez-Antolinez   +4 more
doaj   +1 more source

The Evolution of T Cell Depleted Haploidentical Transplantation

Frontiers in Immunology, 2019
Work on bone marrow transplantation from haploidentical donor has been proceeding for over 20 years all over the world and new transplant procedures have been developed. To control both graft rejection and graft vs.
Franco Aversa, Antonio Pierini, Loredana Ruggeri, Massimo Fabrizio Martelli, Andrea Velardi   +4 more
doaj   +1 more source

Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]

, 2012
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Yumi Matsuzaki, Yoko Ogawa, Shigeto Shimmura, Yo Mabuchi, Sadafumi Suzuki, Yutaka Kawakami, Shinichiro Okamoto, Hideyuki Okano, Takaaki Inaba, Satoru Morikawa, Saori Yaguchi, Kazuo Tsubota, Tomonori Yaguchi   +12 more
core  

Immune reconstitution and graft-versus-host reactions in rat models of allogeneic hematopoietic cell transplantation

Frontiers in Immunology, 2012
Allogeneic hematopoietic cell transplantation (alloHCT) extends the lives of thousands of patients who would otherwise succumb to hematopoietic malignancies such as leukemias and lymphomas, aplastic anemia and disorders of the immune system.
Severin eZinöcker, Severin eZinöcker, Ralf eDressel, Xiao-Nong eWang, Anne Mary Dickinson, Bent eRolstad   +5 more
doaj   +1 more source

Graft-versus-Host Disease: Review

, 2019
Graft-versus-host Disease (GVHD) is a major complication with high morbidity and mortality rates on patients undergoing hematopoietic stem cell transplantation.
Tulio Batista Abud (6543074), Antonio Di Zazzo (827192), Lauro Augusto de Oliveira (4958032), Luciene Barbosa de Sousa (4958035)   +3 more
core   +1 more source

Ruxolitinib in refractory acute and chronic graft-versus-host disease: a multicenter survey study

, 2020
Graft-versus-host disease is the main cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation. First-line treatment is based on the use of high doses of corticosteroids.
López Corral, Lucía, Escamilla Gómez, Virginia, García Cadenas, Irene, Caballero Velázquez, Teresa, Pérez Martínez, Ariadna, Pérez Simón, José Antonio, Espigado Tocino, Ildefonso, Márquez Malaver, Francisco J., García-Gutiérrez, Valentín   +8 more
core   +1 more source

Selective allodepletion to improve anti-viral and anti-leukaemic responses after haploidentical transplantation [PDF]

, 2009
Immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical SCT, but infection and leukaemic relapse remain problematic.
Samarasinghe, S, Samarasinghe, S.
core  

Severe Liver Dysfunction after Donor Lymphocyte Infusion for Relapsed Multiple Myeloma

The Korean Journal of Gastroenterology
Donor lymphocyte infusion (DLI) is performed to augment an anti-tumor immune response or ensure donor stem cells remain engrafted following allogeneic stem cell transplantation but may induce graft-versus-host disease (GVHD) involving skin, intestine ...
Tae-Hoon No, Nae-Yun Heo, Seung Ha Park, Joon Hyuk Choi, Junghwan Lee, Sung Nam Lim, Seon Yang Park   +6 more
doaj   +1 more source

Activated CD4 + T lymphocyte is a potential biomarker for acute graft-vs.-host disease after hematopoietic stem cell transplantation in children with transfusion-dependent β-thalassemia

Frontiers in Pediatrics, 2022
BackgroundAcute graft-vs.-host disease (aGVHD) is still one of the most common and life-threatening complications of allogeneic hematopoietic stem cell transplantation (HSCT).
Ken Huang, Jianming Luo
doaj   +1 more source

Glutathione S-transferase A1 polymorphisms and acute graft-vs.-host disease in HLA-matched sibling allogeneic hematopoietic stem cell transplantation

, 2007
Busulfan and the metabolites of cyclophosphamide are conjugated with glutathione and catabolized by enzymes of the cytosolic glutathione S-transferases family.
Lee, Kyung-Hun, Kim, Inho, Keam, Bhumsuk, Park, Sung Sup, Ra, Eun Kyung, Kim, Jin Hee, Park, Seonyang, Kim, Byoung Kook, Hong, Yun-Chul, Yoon, Sung-Soo, Kim, Chul Soo, Oh, So Yeon   +11 more
core   +1 more source