Results 221 to 230 of about 4,936,870 (299)

Does a Loading Dose Improve Outcomes? Colistin Therapy for Urinary Tract Infections Caused by Multidrug-Resistant Gram-Negative Bacteria. [PDF]

Antibiotics (Basel)
Katip W, Taruangsri P, Okonogi S, Lee SWH, Rayanakorn A.   +4 more
europepmc   +1 more source

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang, Xin‐Yu Ding, Mei‐Ping Lu, Yan‐Bing Chen, Ye Yuan, Lin Jiang, Min Zhang, Lei Cheng   +7 more
wiley   +1 more source

Incidence proportion and divergent performance of risk factors for carbapenem-resistant Gram-negative bacteria bloodstream infections across haematological cohorts. [PDF]

JAC Antimicrob Resist
Maestro-de la Calle G, Calbacho M, Mateo Flores J, Sáez-Marín AJ, Alonso-Crespo A, Gil-Manso R, García-González C, Viedma E, Caro-Teller JM, Carpeño Fernández L, Lizasoain-Hernández M.   +10 more
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

Architecture of the Wza-Wzc complex that mediates colanic acid translocation across the cell envelope in Gram-negative bacteria. [PDF]

Nat Commun
Liu J, Han Y, Huang G, Zhang M, Du J, Zhou H, Chen D, Huang Y.   +7 more
europepmc   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Prevalence and molecular characterization of colistin-resistant gram-negative bacteria from a tertiary care hospital in Eastern India. [PDF]

BMC Microbiol
Singh S, Sahoo RK, Behera IC, Sahoo BN, Barik P, Sahu MC, Pati S.   +6 more
europepmc   +1 more source

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

Advanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria, Amy Gelmi, Peter C. Sherrell, Stefan Di Medio, Nhiem Tran, Kate Fox   +5 more
wiley   +1 more source

De Novo Design of Membrane-Targeting Antimicrobial Peptides Against Gram-Negative Bacteria Using a Generative Artificial Intelligence Framework. [PDF]

Adv Sci (Weinh)
Yu J, Sun DW, Wei Q, Zhang Y, Tang J, Pu H.   +5 more
europepmc   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source