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Colistin Resistance in Gram-Negative Bacteria: Mechanisms, Transmission, and Novel Intervention Strategies. [PDF]

open access: yesMicroorganisms
Zeb S   +9 more
europepmc   +1 more source

Gram-Negative Bacteria

2011
Aeromonas species are gram-negative anaerobic rods found in fresh water lakes and streams. They have also been recovered from chlorinated tap water, including hospital water supplies. Aeromonas infections of freshwater traumatic wounds cause a characteristic clinical picture indistinguishable from group A streptococcal infection in normal hosts ...
Marc E. Grossman   +3 more
  +4 more sources

Leukotoxins of gram-negative bacteria

Veterinary Microbiology, 2002
Leukotoxins are a group of exotoxins that produce their primary toxic effects against leukocytes, especially polymorphonuclear cells (PMNs). Leukotoxins include a variety of chemicals ranging from 9,10-epoxy 12-octadecenoate, a fatty acid derivative secreted by leukocytes themselves, to proteins such as RTX (repeats in toxin).
Sanjeev Kumar, Narayanan   +3 more
openaire   +2 more sources

Antibiotic uptake into gram-negative bacteria

European Journal of Clinical Microbiology & Infectious Diseases, 1988
Antibiotics taken up into gram-negative bacteria face two major diffusion barriers, the outer and cytoplasmic membranes. Of these, the former has been most studied and is discussed in detail here. Evidence from antibiotic MIC studies on porin-deficient mutants compared with their porin-sufficient parent strains has provided strong support for the ...
R E, Hancock, A, Bell
openaire   +2 more sources

Resistance mechanisms in Gram-negative bacteria

Medicina Intensiva (English Edition), 2022
Enterobacterales resistant to carbapenems or producing extended-spectrum β-lactamases (ESBL) and non-fermenters resistant to carbapenems present resistance to many of the antimicrobials commonly used in clinical practice, and have been recognized by the World Health Organization as a critical priority for the development of new antimicrobials.
Lepe, José A.   +1 more
openaire   +3 more sources

Resistance in gram-negative bacteria: Enterobacteriaceae

American Journal of Infection Control, 2006
The emergence and spread of resistance in Enterobacteriaceae are complicating the treatment of serious nosocomial infections and threatening to create species resistant to all currently available agents. Approximately 20% of Klebsiella pneumoniae infections and 31% of Enterobacter spp infections in intensive care units in the United States now involve ...
openaire   +8 more sources

Gram-Negative Bacteria

2001
The cell wall of Gram-negative bacteria has a very distinctive layered look under the electron microscope and is dramatically different from the Gram-positive cell wall. The inner layer consists of a thin peptidoglycan layer; the outer layer or outer membrane is a protein containing bilayer.
Robert P. Rapp, Kenneth E. Record
openaire   +1 more source

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