Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]
We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad +4 more
core +2 more sources
Post-neurosurgical meningitis; gram negative bacilli vs. gram positive cocci
Background: Post-neurosurgical meningitis is a significant cause of mortality and morbidity. In this study we aimed to compare the differences of clinical, laboratory features and outcomes between the post-neurosurgical meningitis caused by gram-negative
Mehdi Zeinalizadeh +7 more
doaj
The common bacterial pathogenes isolated from blood culture in paediatric patients
Fever is a common illness in the pediatric age group ,the causes could be viral ,bacterial and fungal , this study was focused on bacterial pathogens as gram positive like Staphylococci, coagulase positive or negative ,Streptococci and gram ...
Baghdad Science Journal
doaj +1 more source
Conjugation in Gram-Positive Bacteria
ABSTRACT Conjugative transfer is the most important means of spreading antibiotic resistance and virulence factors among bacteria. The key vehicles of this horizontal gene transfer are a group of mobile genetic elements, termed conjugative plasmids. Conjugative plasmids contain as minimum instrumentation an origin of transfer (
Nikolaus, Goessweiner-Mohr +3 more
openaire +2 more sources
Antimicrobial Effect of Acacia Nilotica on Some Gram Positive and Gram Negative Bacteria
Acacia nilotica is a plant has an inspiring range of medicinal uses. This plant contributes a number of groups among which are alkaloids, volatile essential oils, phenols and phenolic glycosides, resins, oleosins, steroids, tannins and terpenes, this ...
Faten R. Hameed
doaj +1 more source
Antimicrobial Resistant Bacteria Isolated from Intensive Care Units
Aimed to determine the kind of microorganisms probably to be gifted inside the in-depth care unit and the suitable antibiotics for them. Methods use the duration between October and December 2021.
Eman Muftah Elzouki +3 more
doaj +1 more source
The Role of Bacillithiol in Gram-Positive Firmicutes [PDF]
Significance: Since the discovery and structural characterization of bacillithiol (BSH), the biochemical functions of BSH-biosynthesis enzymes (BshA/B/C) and BSH-dependent detoxification enzymes (FosB, Bst, GlxA/B) have been explored in Bacillus and ...
Antelmann, Haike +3 more
core +1 more source
Timely excision of prophage Φ13 is essential for the Staphylococcus aureus infectious process
Mobile genetic elements play an essential part in the infectious process of major pathogens, yet the role of prophage dynamics in Staphylococcus aureus pathogenesis is still not well understood.
Olivier Poupel +5 more
doaj +1 more source
Background Bacterial bloodstream infection is responsible for the majority of cases of sepsis and septic shock. Early recognition of the causative pathogen is pivotal for administration of adequate empiric antibiotic therapy and for the survival of the ...
Fan Zhang +4 more
doaj +1 more source
Ceragenins and Antimicrobial Peptides Kill Bacteria through Distinct Mechanisms
Ceragenins are a family of synthetic amphipathic molecules designed to mimic the properties of naturally occurring cationic antimicrobial peptides (CAMPs). Although ceragenins have potent antimicrobial activity, whether their mode of action is similar to
Gabriel Mitchell +14 more
doaj +1 more source

