Results 21 to 30 of about 278,994 (250)

Novel Antibiotics for the Treatment of Gram-Positive Bacterial Infections

open access: yesJournal of Medicinal Chemistry, 2002
The natural dipeptide antibiotic TAN 1057 A,B displays excellent antibacterial activity against staphylococci including methicillin resistant Staphylococcus aureus. However, the in vitro activity against additional Gram-positive strains, in particular pneumococci and Enterococcus faecalis, proved to be considerably lower.
Brands, M.   +9 more
openaire   +3 more sources

Nonadherence to treatment recommendations is a factor contributing to the clinical failure of daptomycin: Cohort study in Brazil

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2020
To evaluate the clinical outcomes of daptomycin therapy and adherence to treatment recommendations, a retrospective cohort study was conducted with patients that received daptomycin during the period of the study.
Tathiana Silva de Souza Martins   +5 more
doaj   +1 more source

Unravelling the Differential Host Immuno-Inflammatory Responses to Staphylococcus aureus and Escherichia coli Infections in Sepsis

open access: yesVaccines, 2022
Previous reports from our lab have documented dysregulated host inflammatory reactions in response to bacterial infections in sepsis. Both Gram-negative bacteria (GNB) and Gram-positive bacteria (GPB) play a significant role in the development and ...
Ena Gupta   +7 more
doaj   +1 more source

The growing threat of antibiotic resistance in wound infections: Evidence from tertiary care in Pakistan [PDF]

open access: yesArchives of Biological Sciences, 2023
The present study analyzed 361 non-duplicated wound swab samples from 187 males and 174 females, ranging in age from 0 to 100 years with a mean age of 37.1±1.9 years, and to determine the prevalence of bacterial wound infections and the diversity of ...
Imran Hassan   +4 more
doaj   +1 more source

Construction of a Bacterial Lipidomics Analytical Platform: Pilot Validation with Bovine Paratuberculosis Serum

open access: yesMetabolites, 2023
Lipidomics analyses of bacteria offer the potential to detect and monitor infections in a host since many bacterial lipids are not present in mammals. To evaluate this omics approach, we first built a database of bacterial lipids for representative Gram ...
Paul L. Wood, Erdal Erol
doaj   +1 more source

Bacterial infections in patients with liver cirrhosis and ascites [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Bacterial infections are common complications and the cause of death in patients with cirrhosis and ascites. There is no standard method for a rapid and low-cost diagnosis, and its prognosis is poor. Objective.
Marković-Živković Bojana   +6 more
doaj   +1 more source

Difference of Procalcitonin Levels in Gram-Positive and Gram-Negative Bacterial Sepsis Patients of Indonesia Army Central Hospital Gatot Soebroto in 2016

open access: yesJuxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2022
Introduction: Procalcitonin is known as a marker of infection and indicator for severity of infections. In sepsis, elevated procalcitonin levels in blood have a significant value that can be used as a sepsis biomarker.
Nindy Handayani   +2 more
doaj   +1 more source

EARLY PREDICTION OF GRAM-POSITIVE BACTEREMIA IN FEVERISH EGYPTIAN PATIENTS USING SOME SELECTED INFLAMMATORY MEDIATORS [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2015
Bloodstream infection is an important cause of morbidity and mortality. Some components of the bacterial cell wall bind to receptors on the cell surface of the host monocytes and macrophages and induce cytokines production. This study assessed the levels
Riham Youssef
doaj   +1 more source

Multidrug-Resistant Gram-Positive Bacterial Infections

open access: yesKorean Journal of Medicine, 2015
Antimicrobial resistance threatens the effective treatment of bacterial infections and is a serious problem worldwide. Multidrug-resistant bacteria are difficult to treat and the treatment outcome is worse than with susceptible bacteria. In Korea, the antibiotic resistance rates of the major Gram-positive bacteria methicillin-resistant Staphylococcus ...
Younghee Jung, Hong Bin Kim
openaire   +1 more source

Positive Bacterial Culture among Suspected Orthopedic Infections in a Tertiary Care Centre: A Descriptive Cross-sectional Study

open access: yesJournal of Nepal Medical Association, 2022
Introduction: A hospital-based investigation of bacteriological isolates helps to identify common causative bacteria and their antibiotic sensitivity patterns.
Ishor Pradhan   +4 more
doaj   +1 more source

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