Novel Antibiotics for the Treatment of Gram-Positive Bacterial Infections
The natural dipeptide antibiotic TAN 1057 A,B displays excellent antibacterial activity against staphylococci including methicillin resistant Staphylococcus aureus. However, the in vitro activity against additional Gram-positive strains, in particular pneumococci and Enterococcus faecalis, proved to be considerably lower.
Brands, M. +9 more
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Bacterial infections in patients with liver cirrhosis and ascites [PDF]
Introduction. Bacterial infections are common complications and the cause of death in patients with cirrhosis and ascites. There is no standard method for a rapid and low-cost diagnosis, and its prognosis is poor. Objective.
Marković-Živković Bojana +6 more
doaj +1 more source
Introduction: Procalcitonin is known as a marker of infection and indicator for severity of infections. In sepsis, elevated procalcitonin levels in blood have a significant value that can be used as a sepsis biomarker.
Nindy Handayani +2 more
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Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown +27 more
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The growing threat of antibiotic resistance in wound infections: Evidence from tertiary care in Pakistan [PDF]
The present study analyzed 361 non-duplicated wound swab samples from 187 males and 174 females, ranging in age from 0 to 100 years with a mean age of 37.1±1.9 years, and to determine the prevalence of bacterial wound infections and the diversity of ...
Imran Hassan +4 more
doaj +1 more source
Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard +156 more
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Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC +6 more
core +1 more source
The small quinolone derived compound HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. [PDF]
HT61 is a small quinolone-derived compound previously demonstrated to exhibit bactericidal activity against gram-positive bacteria including methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). When
Amison, RT +6 more
core +1 more source
Antibacterial and anti-quorum sensing activities of selected italian honeys against antibiotic-resistant pathogens [PDF]
Three nectar honeys (eucalyptus, thyme and forest) and two honeydew honeys (fir and Metcalfa) from Italy were tested for their antibacterial activity against pathogens commonly associated with wound and burn infections, including methicillin-resistant ...
Fidaleo, Marco +2 more
core +1 more source
Multidrug-Resistant Gram-Positive Bacterial Infections
Antimicrobial resistance threatens the effective treatment of bacterial infections and is a serious problem worldwide. Multidrug-resistant bacteria are difficult to treat and the treatment outcome is worse than with susceptible bacteria. In Korea, the antibiotic resistance rates of the major Gram-positive bacteria methicillin-resistant Staphylococcus ...
Younghee Jung, Hong Bin Kim
openaire +1 more source

