pH‐Driven Two‐Stage Conformational Switching Activates an Acid‐Responsive Chaperone
AchC is an ATP‐independent, pH‐responsive chaperone. AchC functions as a molecular switch, sensing pH changes and undergoing a two‐stage conformational transition: C‐terminal extension (colored in yellow) loosening at mild pH 4.0–5.5 and monomerization at strong acidic pH 3.0.
Soojeong Ham +4 more
wiley +2 more sources
Antibiotic resistance among Gram-negative bacteria in bloodstream infections in Shiraz, Iran (2012-2023). [PDF]
Nejati Boor Boor MH +10 more
europepmc +1 more source
Magnetic Resonance Reveals Radical Stability in Native Biofilms and Its Role in Bacterial Resistance
The complex biofilm environment consists of planktonic bacterial cells and cells embedded in an extracellular matrix (ECM). Through an integrated magnetic resonance approach, we show that nitroxide radicals primarily interact with the polysaccharides and lipids in the ECM.
Alysia Mandato +10 more
wiley +2 more sources
GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis. [PDF]
Bennison DJ +20 more
europepmc +1 more source
Gram-negative bacteria resistant to commonly used antibiotics from wastewater within a hospital building. [PDF]
Brown S, Best E, Kirby A.
europepmc +1 more source
Life Cycle Plasticity of Colpoda aspera Fed With Petroleum Tolerant Gram-Positive and Gram-Negative Bacteria. [PDF]
Mondragón-Camarillo L +2 more
europepmc +1 more source
Transthyretin is a novel innate immune effector against Gram negative bacteria. [PDF]
Bernabé T +7 more
europepmc +1 more source
<i>Caenorhabditis elegans</i> as an In Vivo Infection-Rescue Model for Early-Stage Antimicrobial Screening Against Gram-Positive and Gram-Negative Bacteria. [PDF]
Mirza S, McClure JA, Conly JM, Zhang K.
europepmc +1 more source

