Results 81 to 90 of about 109,990 (268)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

Deformation Driven Suction Cups: A Mechanics‐Based Approach to Wearable Electronics

open access: yesAdvanced Science, EarlyView.
Deformation‐driven suction cups enable robust, reversible adhesion of wearable electronics to human skin spanning wide mechanical compliance, without adhesives or tight straps. By integrating mechanics modeling, experiments, and contact mechanics theory, this work reveals how cup geometry, substrate compliance, and interfacial adhesion govern suction ...
Seola Lee   +10 more
wiley   +1 more source

3D‐Printed Architected Anisotropic Channels for Ultrafast Solar‐Driven Interfacial Evaporation via Localized Thermal Management and Water Layer Structuring

open access: yesAdvanced Science, EarlyView.
A 3D‐printed anisotropic channel evaporator integrates directional geometry with aligned titanium oxide, boron nitride, and chitosan networks to coordinate photon absorption, heat localization, and water transport. Phonon‐guided thermal pathways and interfacial water structuring enable ultrahigh evaporation rates and long‐term salt‐resistant solar ...
Sijia Sun   +9 more
wiley   +1 more source

Steps towards inclusivity: modifying challenging content, navigating pedagogical materials and initiating student reflection within the Classics classroom

open access: yesThe Journal of Classics Teaching
Although there is plenty of scholarship regarding the concerns of addressing controversial and sensitive subject manner in the Classics classroom, and I have considered these to quite an extent, my own interest in these practices emerged where they ...
David Peddar
doaj   +1 more source

Microglial Membranes Wrapped Ultrasmall Medium‐Entropy Ru Single‐Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li   +17 more
wiley   +1 more source

Life against algorithmic management: a study on burnout and its influencing factors among food delivery riders

open access: yesFrontiers in Public Health
BackgroundWith the rapid development of global digital economy, burnout among food delivery riders has become an important public health issue. Although burnout has been widely studied, research on burnout among food delivery riders, particularly the ...
Jian Dong, Guoyong Zhang, Lizhi Wu
doaj   +1 more source

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

open access: yesAdvanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li   +10 more
wiley   +1 more source

Regioisomeric Effects on Enhancing p‐Type Characteristics of Self‐Assembled Molecules in Inverted Perovskite Solar Cells

open access: yesAdvanced Science, EarlyView.
Regioisomeric effects are a critical design parameter in self‐assembled monolyaer (SAM) engineering, underscoring their importance for optimizing buried interface properties and advancing the performance and stability of inverted perovskite solar cells.
Myeong‐Ho Hong   +5 more
wiley   +1 more source

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