Results 61 to 70 of about 119,582 (346)
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Thinking the Unthinkable: An Alternative Route to a Unified Theory
PhilosophiesOne of the greatest quests in physics in current times is the search for a grand unified theory—to bring all the forces of nature into one coherent explanatory framework.
Julian Hart
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Nuclear Physics B, 2021 We consider a non-supersymmetric E6 Grand Unified Theory (GUT) with intermediate trinification symmetry SU(3)C×SU(3)L×SU(3)R×D (D denoted as D-parity for discrete left-right symmetry) and study the effect of one-loop threshold corrections arising due to ...
Chandini Dash +3 more
doaj +1 more source
, 2019 The author Wan-Chung Hu(born1973) is a MD (National Taiwan University) and PhD (Johns Hopkins University). This book contains theories in physics, chemistry, biology, geosciences, and mathematics. Spinity is a force to drag spacetime to rotate around central mass.
openaire +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Tri-unification: a separate SU(5) for each fermion family
Journal of High Energy PhysicsIn this paper we discuss SU(5)3 with cyclic symmetry as a possible grand unified theory (GUT). The basic idea of such a tri-unification is that there is a separate SU(5) for each fermion family, with the light Higgs doublet(s) arising from the third ...
Mario Fernández Navarro +2 more
doaj +1 more source
A new flavour imprint of SU(5)-like grand unification and its LHC signatures
Physics Letters B, 2015 We point out that the hypothesis of an SU(5)-like supersymmetric Grand Unified Theory (GUT) implies a generic relation within the flavour structure of up-type squarks. Contrary to other well-known SU(5) relations between the down-quark and charged lepton
S. Fichet, B. Herrmann, Y. Stoll
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Grand unified theory with a stable proton [PDF]
International Journal of Modern Physics A, 2018 We demonstrate that a phenomenologically viable four-dimensional grand unified theory with no proton decay can be constructed. This is done in the framework of the minimal nonsupersymmetric SU(5) GUT by introducing new representations and separating the physical quark and lepton fields into different multiplets.
Fornal, Bartosz, Grinstein, Benjamín
openaire +4 more sources