The effects of bipolar disorder granule cell hyperexcitability and lithium therapy on pattern separation in a computational model of the dentate gyrus. [PDF]
Transl PsychiatrySingh S +5 more
europepmc +1 more source
Tetrodotoxin prevents heat-shock induced granule cell dispersion in hippocampal slice cultures. [PDF]
Front Cell Dev Biol, 2022 Ahrari A, Meseke M, Förster E.
europepmc +1 more source
Oxytocin enhances excitability and potentiates synaptic transmission in dentate gyrus granule cells
Alyssa Marron +2 more
openalex +2 more sources
PANETH CELL GRANULE OF MOUSE INTESTINE [PDF]
The Journal of Cell Biology, 1962 H M, SELZMAN, R A, LIEBELT
openaire +2 more sources
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Advanced Science, EarlyView.Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth. [PDF]
Sci RepTsiami F +8 more
europepmc +1 more source
Teaching NeuroImage: Cerebellar Atrophy Due to JC Virus Granule Cell Neuronopathy: A Clinical Syndrome Distinct From Classic PML. [PDF]
Neurology, 2023 Silva-Rosas C +3 more
europepmc +1 more source
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Shank3 establishes AMPA receptor subunit composition at cerebellar mossy fiber-granule cell synapses and is associated with altered regional microglial morphology. [PDF]
Neurobiol DisKshetri R, Al Aameri RFH, Richardson BD.
europepmc +1 more source
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. [PDF]
Mol Brain, 2023 Cheng Q +12 more
europepmc +1 more source