Results 91 to 100 of about 125,553 (184)

Advances in the design and development of oncolytic measles viruses. [PDF]

, 2015
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian, Raffel, Corey, Studebaker, Adam W   +2 more
core   +1 more source

Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding [PDF]

, 2017
There continues to be a major effort in the United States to develop mitigators for the treatment of mass casualties that received high-intensity acute ionizing radiation exposures from the detonation of an improvised nuclear device during a radiological
Dynlacht, Joseph R., Garrett, Joy, Joel, Rebecca, Lane, Katharina, Mendonca, Marc S., Orschell, Christie M.   +5 more
core   +1 more source

Whole Lung Lavage in Autoimmune Pulmonary Alveolar Proteinosis: Unique Challenges in a Resource‐Limited Setting

Clinical Case Reports
Autoimmune pulmonary alveolar proteinosis (PAP) is characterized by antibodies to granulocyte–macrophage colony‐stimulating factor (GM‐CSF), alveolar macrophage dysfunction, and surfactant accumulation.
Ashesh Dhungana, Buddhi Sagar Lamichhane, Prajowl Shrestha, Deepa Kumari Shrestha, Ritamvara Oli, Shreya Dhungana, Pratibha Bista   +6 more
doaj   +1 more source

Role of Granulocyte-Macrophage Colony-Stimulating Factor in Acute Myeloid Leukemia/Myelodysplastic Syndromes

Journal of Global Oncology, 2017
Purpose: Granulocyte-macrophage colony-stimulating factor (GM-CSF) cytokine stimulates growth, differentiation, and function of myeloid progenitors. We aimed to study the role of GM-CSF gene expression, its protein, and antibodies in patients with acute ...
Neemat M. Kassem, Alya M. Ayad, Noha M. El Husseiny, Doaa M. El-Demerdash, Hebatallah A. Kassem, Mervat M. Mattar   +5 more
doaj   +1 more source

含柴胡的草藥對人類淋巴細胞的影響 [PDF]

, 2001
Bupleurum-containing compounds, such as KY88 Liver Livo are thought to have immunomodulatory effects. This study investigated the effects of KY88 Liver Livo on the mitogenic induction of lymphocytes in vitro.
Chow, LWC, Loo, TY, Sham, JST
core  

Directs effects of granulocyte-macrophage colony stimulating factor (GM-CSF) on adaptive immunogenesis

Human Vaccines & Immunotherapeutics, 2019
Background: We studied direct effects of human granulocyte-macrophage colony stimulating factor (GM-CSF) on phenotypical characteristics and cytokine-production of non-activated and activated human monocytes/macrophages (Mc/Mphs) and T cells.
Victor Ivanovich Seledtsov, Vladimir V. Malashchenko, Natalja D. Gazatova, Maksim E. Meniailo, Ekaterina M. Morozova, Galina V. Seledtsova   +5 more
doaj   +1 more source

Colony-stimulating factors detected in tumor cells and voided urine are potential prognostic markers for patients with muscle-invasive bladder cancer undergoing radical cystectomy

Research and Reports in Urology, 2018
Yosuke Morizawa,1 Makito Miyake,1 Keiji Shimada,2 Shunta Hori,1 Yoshihiro Tatsumi,1 Yasushi Nakai,1 Nobumichi Tanaka,1 Tomomi Fujii,3 Kiyohide Fujimoto1 1Department of Urology, Nara Medical University, Nara, Japan; 2Department of Pathology, Nara City ...
Morizawa Y, Miyake M, Shimada K, Hori S, Tatsumi Y, Nakai Y, Tanaka N, Fujii T, Fujimoto K   +8 more
doaj  

Impaired granulocyte-macrophage colony-stimulating factor bioactivity accelerates surgical recurrence in ileal Crohn’s disease [PDF]

, 2018
Bonkowski, Erin, Chalk, Claudia, Denson, Lee, Gathungu, Grace, Krumsiek, Julia, Li, Ellen, Newberry, Rodney, Nix, Billy, Rowehl, Leahana, Tian, Xinyu, Trapnell, Bruce, Zhang, Yuanhao, Zhu, Wei   +12 more
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The efficacy of recombinant thrombopoietin in murine and nonhuman primate models for radiation-induced myelosuppression and stem cell transplantation [PDF]

, 1998
Radiation-induced pancytopenia proved to be a suitable model system in mice and rhesus monkeys for studying thrombopoietin (TPO) target cell range and efficacy.
Eaton, D.L., Fielder, P.J., Hartong, S.C.C. (Simone), Neelis, K.J. (Karen), Thomas, G.R. (Roger), Wagemaker, G. (Gerard), Wognum, A.W. (Albert)   +6 more
core   +1 more source

Identification of genes involved in leukaemia and differentiation induced by activated mutants of the GM-CSF receptor β subunit. [PDF]

, 2005
Interleukin (IL)-3, IL-5 and granulocyte-macrophage-colony-stimulating factor (GM-CSF) are cytokines that affect the growth, survival and differentiation of many cells within the haematopoietic system.
Reynolds, Brenton James
core   +1 more source