Results 11 to 20 of about 137,917 (100)

Inhibition of Arginase 1 Liberates Potent T Cell Immunostimulatory Activity of Human Neutrophil Granulocytes

open access: yesFrontiers in Immunology, 2021
Myeloid cell arginase-mediated arginine depletion with consecutive inhibition of T cell functions is a key component of tumor immune escape. Both, granulocytic myeloid-derived suppressor cells (G-MDSC) and conventional mature human polymorphonuclear ...
Verena Vonwirth   +17 more
doaj   +1 more source

Lipocalin-2 Functions as Inhibitor of Innate Resistance to Mycobacterium tuberculosis

open access: yesFrontiers in Immunology, 2018
Lipocalin-2 is a constituent of the neutrophil secondary granules and is expressed de novo by macrophages and epithelium in response to inflammation. Lipocalin-2 acts in a bacteriostatic fashion by binding iron-loaded siderophores required for bacterial ...
Sara Louise Dahl   +9 more
doaj   +1 more source

Bivalve Haemocyte Subpopulations: A Review

open access: yesFrontiers in Immunology, 2022
Bivalve molluscs stand out for their ecological success and their key role in the functioning of aquatic ecosystems, while also constituting a very valuable commercial resource. Both ecological success and production of bivalves depend on their effective
Nuria R. de la Ballina   +5 more
doaj   +1 more source

Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients

open access: yesFrontiers in Oncology, 2013
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Thomas eLehrnbecher   +3 more
doaj   +1 more source

Role of Diacylglycerol Kinases in Acute Myeloid Leukemia

open access: yesBiomedicines, 2023
Diacylglycerol kinases (DGKs) play dual roles in cell transformation and immunosurveillance. According to cancer expression databases, acute myeloid leukemia (AML) exhibits significant overexpression of multiple DGK isoforms, including DGKA, DGKD and ...
Teresa Gravina   +10 more
doaj   +1 more source

Amphibian (Xenopus laevis) Interleukin-8 (CXCL8): A Perspective on the Evolutionary Divergence of Granulocyte Chemotaxis

open access: yesFrontiers in Immunology, 2018
The glutamic acid-leucine-arginine (ELR) motif is a hallmark feature shared by mammalian inflammatory CXC chemokines such the granulocyte chemo-attractant CXCL8 (interleukin-8, IL-8). By contrast, most teleost fish inflammatory chemokines lack this motif.
Daphne V. Koubourli   +3 more
doaj   +1 more source

FORMING OF SOME ORGANS OF HEMATOPOIESIS IN PRE-LARVAE, LARVAE AND FRY OF COMMON BREAM (ABRAMIS BRAMA L.)

open access: yesИзвестия ТИНРО, 2019
Ability for hematopoiesis of spleen, intestinal mucosa, and liver is investigated for early ontogenesis of common bream Abramis brama L., a species of bony fish widespread in the Russian waters, including Astrakhan region.
D. R. Svetasheva, M. P. Grushko
doaj   +1 more source

Review: Relationships between metabolism and neutrophil function in dairy cows in the peripartum period

open access: yesAnimal, 2020
Aspects of neutrophil function are diminished or dysregulated in dairy cows in the weeks just before and after calving, which appears to be an important contributor to the occurrence of retained placenta, mastitis, metritis and endometritis.
S.J. LeBlanc
doaj   +1 more source

Secretory Leukocyte Protease Inhibitor Is Present in Circulating and Tissue-Recruited Human Eosinophils and Regulates Their Migratory Function

open access: yesFrontiers in Immunology, 2022
Eosinophils and secretory leukocyte protease inhibitor (SLPI) are both associated with Th2 immune responses and allergic diseases, but whether the fact that they are both implicated in these conditions is pathophysiologically related remains unknown ...
Oktawia Osiecka   +11 more
doaj   +1 more source

Current Understanding of the Neutrophil Transcriptome in Health and Disease

open access: yesCells, 2021
Neutrophils are key cells of the innate immune system. It is now understood that this leukocyte population is diverse in both the basal composition and functional plasticity.
Luke W. Garratt
doaj   +1 more source

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