Results 21 to 30 of about 137,917 (100)

Neutrophil Functional Heterogeneity: Identification of Competitive Phagocytosis

Frontiers in Immunology, 2017
IntroductionPhagocytosis by neutrophils is a key process in the innate immune response against invading microorganisms. Despite reported heterogeneity in other neutrophils functions, little is known regarding differences in phagocytosis by individual ...
Pien Hellebrekers, Pien Hellebrekers, Falco Hietbrink, Nienke Vrisekoop, Luke P. H. Leenen, Leo Koenderman   +5 more
doaj   +1 more source

The lasting influence of LSD1 in the blood

eLife, 2013
An enzyme called LSD1 that controls the development of blood cells by manipulating gene expression in progenitor cells could be a therapeutic target for leukemia.
Sharon YR Dent, Joya Chandra
doaj   +1 more source

Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma

Frontiers in Oncology, 2023
Hematologic malignancies, including multiple myeloma (MM), promote systemic immune dysregulation resulting in an alteration and increased plasticity of myeloid cell subsets. To determine the heterogeneity of the myeloid cell compartment in the peripheral
Krystle L. Ong, Marcus D. Davis, Kalyn K. Purnell, Hannah Cutshall, Harish C. Pal, Ashley N. Connelly, Christian X. Fay, Valeriya Kuznetsova, Elizabeth E. Brown, Elizabeth E. Brown, Zdenek Hel, Zdenek Hel, Zdenek Hel   +12 more
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Surgical manipulation compromises leukocyte mobilisation responses and inflammation after experimental cerebral ischaemia in mice

Frontiers in Neuroscience, 2014
Acute brain injury results in peripheral inflammatory changes, although the impact of these processes on neuronal death and neuroinflammation is currently unclear.
Adam eDenes, Adam eDenes, JESUS MIGUEL PRADILLO, Caroline eDrake, Hannah eBuggey, Nancy J Rothwell, Stuart M Allan   +6 more
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Silibinin Upregulates CXCR4 Expression in Cultured Bone Marrow Cells (BMCs) Especially in Pulmonary Arterial Hypertension Rat Model

Cells, 2020
Previously we reported that silibinin ameliorated pulmonary arterial hypertension (PAH) in rat PAH models, possibly through the suppression of the CXCR4/SDF-1, until the point where PAH became a severe and irreversible condition.
Tingting Zhang, Nanako Kawaguchi, Kunikazu Tsuji, Emiko Hayama, Yoshiyuki Furutani, Hisashi Sugiyama, Toshio Nakanishi   +6 more
doaj   +1 more source

Increased CD11b and Decreased CD62L in Blood and Airway Neutrophils from Long-Term Smokers with and without COPD

Journal of Innate Immunity, 2020
There is incomplete mechanistic understanding of the mobilization of neutrophils in the systemic and local compartment in smokers with chronic obstructive pulmonary disease (COPD).
Marit Stockfelt, Karin Christenson, Anders Andersson, Lena Björkman, Médea Padra, Bettina Brundin, Koustav Ganguly, Helga Asgeirsdottir, Sara Lindén, Ingemar Qvarfordt, Johan Bylund, Anders Lindén   +11 more
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Granulocytes Acquire Antiapoptosis Activity and Promote Tumor Growth during Tumor Progress

Global Medical Genetics, 2021
Granulocytes play important roles in cancer, and their apoptotic status is often changed by the influence of tumor environment. However, the changes and the function on granulocyte apoptosis in cancer are unclear.
Han Li, Wenyan Shen, Yanjie Xu, Zien Wang, Linghao Wang, Zequn Ding, Zhiyuan Xie, Yan Zhang   +7 more
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Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat

Frontiers in Immunology, 2019
Dendritic cell activating receptor-1 (DCAR1) is a cell-surface receptor encoded by the Antigen Presenting Lectin-like gene Complex (APLEC). We generated a mouse monoclonal antibody against rat DCAR1, and used this to characterize receptor expression and ...
Michael R. Daws, Britt Nakken, Ana Lobato-Pascual, Régis Josien, Régis Josien, Erik Dissen, Sigbjørn Fossum   +6 more
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Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids

Frontiers in Cellular and Infection Microbiology, 2021
Neutrophil migration from blood to tissue-residing microbes is governed by a series of chemoattractant gradients of both endogenous and microbial origin. Periodontal disease is characterized by neutrophil accumulation in the gingival pocket, recruited by
Agnes Dahlstrand Rudin, Arsham Khamzeh, Vignesh Venkatakrishnan, Tishana Persson, Michael Gabl, Otto Savolainen, Huamei Forsman, Claes Dahlgren, Karin Christenson, Johan Bylund   +9 more
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Effect of fungicidal contamination on survival, morphology, and cellular immunity of Apis mellifera (Hymenoptera: Apidae)

Frontiers in Physiology, 2023
Pesticide residues have been reported in hive-stored products for long periods. Larvae of honey bees experience oral or contact exposure to these products during their normal growth and development inside the cells.
Gurleen Kaur, Amandeep Singh, Rohit Sharma, Abhinay Thakur, Shushant Tuteja, Shyamli, Randeep Singh   +6 more
doaj   +1 more source