Results 161 to 170 of about 189,801 (353)
Pediatric Discovery, EarlyView.Our study demonstrates elevated GITRL expression in HDM‐exposed dendritic cells (in vitro), murine asthma models, and pediatric asthma patients, and reveals a direct association between GITRL levels and disease severity in children. ABSTRACT Currently, there are no reliable pediatric biomarkers for assessing the severity of asthma. Therefore, the study
Yuehan Li +7 more
wiley +1 more source
Characterization of the clinical effects after the first dose of bacterially synthesized recombinant human granulocyte-macrophage colony- stimulating factor [PDF]
, 1989 Graham J. Lieschke +2 more
openalex +1 more source
Developing New Drugs for the COVID‐19 Emergency: Anatomy of the U.S. Response
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.ABSTRACT Context To meet the need for effective treatments during the COVID‐19 Public Health Emergency, the U.S. government sought to accelerate the discovery and development of new antiviral treatments—a process that normally took 4–12 years.
Thomas J. Moore +2 more
wiley +1 more source
Induction of proliferation of purified human myeloid progenitor cells: a rapid assay for granulocyte colony-stimulating factors [PDF]
, 1984 JD Griffin +4 more
openalex +1 more source
Artificial Intelligence and the Evolving Landscape of Immunopeptidomics
PROTEOMICS – Clinical Applications, EarlyView.ABSTRACT Background Immunopeptidomics is the large‐scale study of peptides presented by major histocompatibility complex (MHC) molecules and plays a central role in neoantigen discovery and cancer immunotherapy. However, the complexity of mass spectrometry data, the diversity of peptide sources, and variability in immune responses present major ...
Thanh Hoa Vo +4 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Granulocyte-macrophage colony-stimulating and binding activities of purified human urinary colony-stimulating factor to murine and human bone marrow cells [PDF]
, 1982 K Motoyoshi +4 more
openalex +1 more source
Efficacy of Early Switching From Docetaxel to Cabazitaxel in Castration‐Resistant Prostate Cancer
The Prostate, EarlyView.ABSTRACT Background Cabazitaxel is a taxane agent associated with fewer symptomatic adverse events than docetaxel in treating castration‐resistant prostate cancer (CRPC), yet it is typically reserved for post‐docetaxel failure. This study assessed whether early switching from docetaxel to cabazitaxel could improve clinical outcomes.
Taketo Kawai +13 more
wiley +1 more source