Results 111 to 120 of about 134,623 (343)

Idiotype protein vaccination in combination with adjuvant cytokines in patients with multiple myeloma - evaluation of T-cell responses by different read-out systems

Haematologica, 2007
Anti-idiotypic T cells were analyzed in myeloma patients (n=18) vaccinated with idiotypic protein together with the adjuvant cytokines granulocyte-macrophage colony-stimulating factor (GM-CSF) and/or interleukin-12 (IL-12).
Amir Osman Abdalla, Lotta Hansson, Ingrid Eriksson, Barbro Näsman-Glaser, Eva D. Rossmann, Hodjattallah Rabbani, Håkan Mellstedt, Anders Österborg   +7 more
doaj   +1 more source

Cancer-Associated Fibroblasts Neutralize the Anti-tumor Effect of CSF1 Receptor Blockade by Inducing PMN-MDSC Infiltration of Tumors. [PDF]

, 2017
Tumor-associated macrophages (TAM) contribute to all aspects of tumor progression. Use of CSF1R inhibitors to target TAM is therapeutically appealing, but has had very limited anti-tumor effects.
Albert Lo, Andrey Loboda, Ashani T. Weeraratna, Ayumi Hashimoto, Brian Nam, Butowski, Carus, Challacombe, Chao, Charles Mulligan, Chunsheng Zhang, Condamine, Conway, Coussens, David W. Speicher, DeNardo, Dmitry I. Gabrilovich, Douglas Marvel, Ellen Puré, Fang Wang, Fearon, Feig, Finke, Fred Denstman, Gabrilovich, Gabrilovich, Gascard, Genovese, Gentles, Greenberg, Grivennikov, Guleria, Huang, Kato, Kumar, Ladanyi, Laxminarasimha Donthireddy, Lin, Linda A. Snyder, Lo, Lokeshwar, Lucas, Lucia R. Languino, MacDonald, Manuel A. Sepulveda, Mao, Marlee A. Goins, Messmer, Meyer, Mishra, Mitchem, Mok, Mok, Neil Hockstein, Newman, Noman, Obermajer, Ohno, Orimo, Peter Ordentlich, Pixley, Prashanthi Vonteddu, Pyonteck, Qin Liu, Ramachandran, Reeti Behera, Ries, Ries, Robert H. Vonderheide, Sasse, Sergio Lavilla-Alonso, Shanti Shakamuri, Sionov, Sluijter, Solito, Strachan, Szkandera, Talmadge, Tap, Thomas Condamine, Timothy Chao, Vetsika, Vinit Kumar, Wang, Weber, Xiaowei Xu, Xu, Yang, Zhang, Zhang, Zhu   +90 more
core   +2 more sources

In vivo stimulation of megakaryocytopoiesis by recombinant murine granulocyte-macrophage colony-stimulating factor [PDF]

, 1990
A. M. Vannucchi, Alberto Grossi, D Rafanelli, Ferrini Pr   +3 more
openalex   +1 more source

Iron/Cobalt Dual‐Atom Catalyst Orchestrate Photothermal‐Chemodynamic Immunotherapy Against MRSA: Multi‐Omics Dissection in Murine and Porcine Models

Advanced Science, EarlyView.
FeCo dual‐atom catalyst (FeCo‐N‐DAC) with ultrahigh metal loading (Fe > 5.4%, Co > 4.8%) is developed for synergistic photothermal‐chemodynamic immunotherapy. FeCo‐N‐DAC penetrates deep‐seated tissues, eradicates MRSA biofilms, and reprograms immune‐inflammatory pathways via multi‐omics‐validated mechanisms.
Shihao Xu, Binge Huang, Hao Lin, Jinming Li, Zhaoxiang Lu, Qi Zhang, Jia Li, Shiping Yang, Songsong Lan, Yan Yang, Yun Feng, Xiaojun He   +11 more
wiley   +1 more source

Synovial tissue macrophages: friend or foe? [PDF]

, 2017
Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce ...
Alivernini, Stefano, Kurowska-Stolarska, Mariola   +1 more
core   +2 more sources

Antibody to Mol abrogates the increase in neutrophil phagocytosis and degranulation induced by granulocyte‐macrophage colony‐stimulating factor [PDF]

, 1989
Y. Kletter, Ilan Bleiberg, David W. Golde, Ina Fabian   +3 more
openalex   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Demonstration of early functional compromise of bone marrow derived hematopoietic progenitor cells during bovine neonatal pancytopenia through in vitro culture of bone marrow biopsies [PDF]

, 2012
Background Bovine neonatal pancytopenia (BNP) is a syndrome characterised by thrombocytopenia associated with marked bone marrow destruction in calves, widely reported since 2007 in several European countries and since 2011 in New Zealand. The disease is
Ballingall, Keith T, Bell, Charlotte, Connelly, Maira, Dagleish, Mark P, Laming, Eleanor, Melzi, Eleonora, Rocchi, Mara S, Scholes, Sandra F E, Willoughby, Kim   +8 more
core   +2 more sources

Enhancement of the grafting efficiency of transplanted marrow cells by preincubation with interleukin-3 and granulocyte-macrophage colony- stimulating factor [PDF]

, 1991
Mehdi Tavassoli, M Konno, Yutaro Shiota, Eijiro Omoto, Minguell Jj, ED Zanjani   +5 more
openalex   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source