Results 161 to 170 of about 129,342 (334)

Interleukin-6 and granulocyte-macrophage colony-stimulating factor are candidate growth factors for chronic myelomonocytic leukemia cells [PDF]

, 1989
MP Everson, CB Brown, MB Lilly
openalex   +1 more source

Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration

Cell Proliferation, EarlyView.
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen, Haijun Zhang, Zhaoheng Wang, Daxue Zhu, Yanhu Li, Yizhi Zhang, Dongxin Wang, Shuwei Chen, Huan Liu, Xuewen Kang   +9 more
wiley   +1 more source

New treatment options in the management of IBD – focus on colony stimulating factors

Biologics: Targets & Therapy, 2008
Josué Barahona-Garrido, Jesús K Yamamoto-FurushoInflammatory Bowel Disease Clinic, Department of Gastroenterology, Instituto Nacional de Ciencias Médicas y Nutrición “Salvador Zubirán& ...
Josué Barahona-Garrido, Jesús K Yamamoto-Furusho   +1 more
doaj  

Granulocyte-Macrophage Colony-Stimulating Factor Influence on Soluble and Membrane-Bound ICOS in Combination with Immune Checkpoint Blockade. [PDF]

Cancer Immunol Res, 2023
Li X, Li J, Zheng Y, Lee SJ, Zhou J, Giobbie-Hurder A, Butterfield LH, Dranoff G, Hodi FS.   +8 more
europepmc   +1 more source

Purified murine granulocyte/macrophage progenitor cells express a high-affinity receptor for recombinant murine granulocyte/macrophage colony-stimulating factor.

, 1988
DE Williams, D C Bicknell, L S Park, J E Straneva, Stephanie Cooper, H E Broxmeyer   +5 more
openalex   +1 more source

Aetiopathogenesis of infantile epileptic spasms syndrome and mechanisms of action of adrenocorticotrophin hormone/corticosteroids in children: A scoping review

Developmental Medicine &Child Neurology, EarlyView.
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes, Velda X. Han, Shrujna Patel, Michelle A. Farrar, Deepak Gill, Shekeeb S. Mohammad, Russell C. Dale   +6 more
wiley   +1 more source

Biologic properties in vitro of a recombinant human granulocyte- macrophage colony-stimulating factor [PDF]

, 1986
D Metcalf, C. Glenn Begley, GR Johnson, Nicos A. Nicola, MA Vadas, Angel F. López, DJ Williamson, GG Wong, SC Clark, EA Wang   +9 more
openalex   +1 more source

Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa

Immunology, EarlyView.
Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito, Raquel Duque do Nascimento Arifa, Rafael de Oliveira Bezerra, Carlos Eduardo Dias Igídio, Bárbara Maria de Amorim‐Santos, Anna Clara Paiva de Menezes Santos, Larissa Mendes Barbosa, João Paulo Pezzini Barbosa, Larissa Marcely Gomes Cassiano, Markus Kohlhoff, Micheli Fagundes, Rafaela Ribeiro Álvares Batista, Celso Martins Queiroz‐Junior, Alessandra M. Saliba, Juliana Divina Almeida Raposo, Fernão Castro Braga, Roney Santos Coimbra, Mauro Martins Teixeira, Caio Tavares Fagundes, Danielle G. Souza   +19 more
wiley   +1 more source

Response to inhaled granulocyte-macrophage colony-stimulating factor in patient with mild-to-moderate autoimmune pulmonary alveolar proteinosis-24 months of follow-up. [PDF]

Clin Respir J, 2023
Oterino-Moreira I, Linares-Asensio MJ, Sanz-Márquez S, Pérez-Encinas M.   +3 more
europepmc   +1 more source

Neutrophils in the Bone Marrow Express DEC205, Guiding Their Migration to Inflamed Tissues

Immunology, EarlyView.
In bone marrow, immature neutrophils express high levels of DEC205, necessary to mediate migration through endothelial cell layers in vitro and in vivo. During maturation and migration to peripheral tissues, expression of DEC205 is downregulated. Thus, expression of DEC205 inversely correlates with the maturation of neutrophils and is involved in ...
Shiying Jin, Xuan Lei, Sonali Singh, Alexander Enk, Karsten Mahnke   +4 more
wiley   +1 more source