Results 211 to 220 of about 131,866 (237)
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Current Opinion in Hematology, 1995
Hematopoietic growth factors primarily used in patients with acute myelogenous leukemia after chemotherapy could reduce significantly the neutrophil recovery time in all patients. In high-risk acute myelogenous leukemia, trials also reported a reduction in the incidence of documented infections and early mortality rate.
Gernot Seipelt, Dieter Hoelzer
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Hematopoietic growth factors primarily used in patients with acute myelogenous leukemia after chemotherapy could reduce significantly the neutrophil recovery time in all patients. In high-risk acute myelogenous leukemia, trials also reported a reduction in the incidence of documented infections and early mortality rate.
Gernot Seipelt, Dieter Hoelzer
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Clinical Role of Granulocyte-Macrophage Colony-Stimulating Factor
Hematology/Oncology Clinics of North America, 1989The activity of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) for increasing leukocyte production and enhancing mature neutrophil function has been clearly demonstrated in phase I clinical trials in patients with a variety of hematologic and malignant diseases. The focus of current studies includes determination of optimal
Ronald T. Mitsuyasu, David W. Golde
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Granulocyte-Macrophage Colony-Stimulating Factor and Vasculitis
Annals of Internal Medicine, 1989Excerpt To the Editor:Recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF) is now being widely used in clinical trials.
Joan H. Schiller +2 more
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Annals of Hematology, 1996
The present study was designed to investigate in vivo immunomodulatory properties of hematopoietic growth factors. The influence on the activation of cytokine synthesis and on the expression of surface antigens associated with cellular activation of G-CSF or GM-CSF was investigated in cancer patients receiving these factors.
U. Haus +9 more
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The present study was designed to investigate in vivo immunomodulatory properties of hematopoietic growth factors. The influence on the activation of cytokine synthesis and on the expression of surface antigens associated with cellular activation of G-CSF or GM-CSF was investigated in cancer patients receiving these factors.
U. Haus +9 more
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The Granulocyte-Macrophage Colony-Stimulating Factors [PDF]
, 1986 Haemopoiesis is the process whereby a small population of multipotential stem cells continuously gives rise to a large number of mature blood cells which comprise eight distinct cellular lineages. In normal health, the circulating levels of mature cells are remarkably invariant, suggesting that their production is tightly regulated.
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Colony-Stimulating Factor and the Differentiation of Granulocytes and Macrophages
1977Colony-stimulating factor (GM-CSF), which specifically stimulates mouse bone marrow cells to proliferate and form neutrophil and/or macrophage colonies in semisolid agar cultures (1, 22), has been detected in many biologic fluids (8, 23–26, 30). Most of the sources of GM-CSF are unsuitable for the isolation of this factor and only human urine (30 ...
Antony W. Burgess, Donald Metcalf
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Granulocyte Macrophage—Colony Stimulating Factor and Oral Mucositis
Annals of Pharmacotherapy, 2002OBJECTIVE: To evaluate the effect of granulocyte macrophage—colony stimulating factor (GM-CSF) in patients with oral mucositis. DATA SOURCES: Literature was accessed through MEDLINE (1966–June 2000) and bibliographic searches. DATA SYNTHESIS: Published literature assessing the use of GM-CSF to treat or prevent oral mucositis was analyzed.
Stacey M. Fung, Mary J Ferrill
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Effect of surgery on granulocyte/macrophage colony‐stimulating factor
Journal of Surgical Oncology, 1978AbstractEighteen surgical patients were studied to determine the effect of anesthesia (general or spinal) and surgery on serum and urinary colony‐stimulating factor(s) (CSF). CSF is a leukopoietin that stimulates proliferation of macrophages and granulocytes from bone marrow precursor cells.
Roger S. Foster, Howard D. Reines
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Granulocyte-Macrophage Colony-Stimulating Factor for Cancer Treatment
Oncology, 1994In the 5 years since granulocyte-macrophage colony-stimulating factor (GM-CSF) was first tested clinically, a number of different strategies for its use have been evaluated in patients with malignant disease. These include using GM-CSF to support standard and high-dose chemotherapy, to accelerate myeloid reconstitution following marrow transplantation,
Graham J. Lieschke, Jonathan Cebon
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Current Opinion in Hematology, 1997
The hematopoietic growth factors granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) not only regulate the numbers of circulating neutrophils but also modulate the function of mature cells. Additionally, newly developed neutrophils subsequently released from the bone marrow in response to colony ...
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The hematopoietic growth factors granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) not only regulate the numbers of circulating neutrophils but also modulate the function of mature cells. Additionally, newly developed neutrophils subsequently released from the bone marrow in response to colony ...
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