Macrophage depletion disrupts immune balance and energy homeostasis. [PDF]
Increased macrophage infiltration in tissues including white adipose tissue and skeletal muscle has been recognized as a pro-inflammatory factor that impairs insulin sensitivity in obesity.
Feng, Gen-Sheng +4 more
core +2 more sources
Application of Western Blot for detection of neutrophil apoptosis-related proteins
The aim of this study was to evaluate suitability of using Western Blot for detection of neutrophil apoptosis and neutrophil apoptosis-related proteins, respectively. Neutrophils were isolated from blood of healthy adult donors and incubated with G-CSF
Petr Sláma
doaj +1 more source
Granulocyte Macrophage Colony-Stimulating Factor [PDF]
Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be induced by immunization with a number of myelin antigens. In particular, myelin oligodendrocyte glycoprotein, a central nervous system (CNS)-specific antigen expressed on the myelin surface, is able to induce a paralytic MS-like disease with extensive CNS ...
Jonathan L. McQualter +7 more
openaire +1 more source
Differential fMet-Leu-Phe- and Platelet-activating Factor-induced Signaling Toward Ral Activation in Primary Human Neutrophils [PDF]
We have measured the activation of the small GTPase Ral in human neutrophils after stimulation with fMet- Leu-Phe (fMLP), platelet activating factor (PAF), and granulocyte macrophage-colony stimulating factor and compared it with the activation of ...
Bos, J.L. +5 more
core +2 more sources
Desert dust exposure is associated with adverse respiratory health effects. Desert dust is a complex pollutant mixtures that includes respirable crystalline and amorphous particles, metals, and microbial constituents.
Gerrit Bredeck +3 more
doaj +1 more source
Factores de Crescimento Hematopoiético
SUMÃRIO: Os factores de crescimento hematopoiético (FCH) são glicoproteinas que regulam a proliferação e diferenciação das células sanguÃneas.
Maria De Fátima Miguel Rodrigues +3 more
doaj +1 more source
Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs [PDF]
Modulation of the immune response against tumour cells is emerging as a valuable approach for cancer treatment. Some experimental studies have shown that secretion of colony stimulating factors by cancer cells reduces their tumorigenicity and increases ...
A Suresh +23 more
core +2 more sources
Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes [PDF]
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes.
Esmaeil, Nafiseh +3 more
core +2 more sources
Cloning and eukaryotic expression of chicken granulocyte macrophage colony stimulating factor gene
In order to study the biological characteristics of chicken granulocyte macrophage colony stimulating factor (GM-CSF), Sichuan shandi black-bone chicken GM-CSF was amplified from ConA stimulated peripheral blood lymphocytes using RT-PCR.
TAN Bing +3 more
doaj +1 more source
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano +6 more
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