Results 31 to 40 of about 129,342 (334)

ATP-evoked intracellular Ca2+ responses in M-CSF differentiated human monocyte-derived macrophage are mediated by P2X4 and P2Y11 receptor activation [PDF]

open access: yes, 2019
Tissues differentially secrete multiple colony stimulating factors under conditions of homeostasis and inflammation, orientating recruited circulating monocytes to differentiate to macrophage with differing functional phenotypes.
Akagawa   +5 more
core   +1 more source

Effect in supralethally irradiated rats of granulocyte colony- stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes [PDF]

open access: yes, 1997
We have previously shown the existence of migratory hematopoietic stem cells in adult solid organs. This study demonstrates that granulocyte colony- stimulating factor (G-CSF) and lisofylline, a phosphatidic acid inhibitor that suppresses hematopoiesis ...
Abdul Rao   +23 more
core   +1 more source

Application of Western Blot for detection of neutrophil apoptosis-related proteins

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
The aim of this study was to evaluate suitability of using Western Blot for detection of neutrophil apo­pto­sis and neutrophil apoptosis-related proteins, respectively. Neutrophils were isolated from blood of healthy adult donors and incubated with G-CSF
Petr Sláma
doaj   +1 more source

Single‐Cell Mechanical Characterization of Human Macrophages

open access: yesAdvanced NanoBiomed Research, 2022
Macrophages remodel their mechanics during differentiation toward different subtypes and drastically adapt their shapes during phagocytosis or entry to inflamed tissues.
Tom M. J. Evers   +5 more
doaj   +1 more source

Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs [PDF]

open access: yes
Modulation of the immune response against tumour cells is emerging as a valuable approach for cancer treatment. Some experimental studies have shown that secretion of colony stimulating factors by cancer cells reduces their tumorigenicity and increases ...
A Suresh   +23 more
core   +2 more sources

Lack of effect of the human GM-CSF analog E21R on the survival of primary human acute myeloid leukemia cells [PDF]

open access: yes, 2004
The granulocyte-macrophage colony-stimulating factor (GM-CSF) analog E21R binds to the GM-CSF receptor complex with low affinity and acts as a competitive antagonist.
Grandage, V.L.   +3 more
core   +1 more source

Predictive Diagnosis of Breast Cancer Based on Cytokine Profile

open access: yesEngineering Proceedings, 2023
A predictive model for the early diagnosis of breast cancer based on the concentration of some cytokines in the tumor microenvironment in the blood was built in this paper.
Marina Barulina   +5 more
doaj   +1 more source

Differential fMet-Leu-Phe- and Platelet-activating Factor-induced Signaling Toward Ral Activation in Primary Human Neutrophils [PDF]

open access: yes, 1999
We have measured the activation of the small GTPase Ral in human neutrophils after stimulation with fMet- Leu-Phe (fMLP), platelet activating factor (PAF), and granulocyte macrophage-colony stimulating factor and compared it with the activation of ...
Bos, J.L.   +5 more
core   +2 more sources

Granulocyte macrophage colony stimulating factor (GM-CSF) biological actions on human dermal fibroblasts

open access: yesEuropean Journal of Histochemistry, 2009
Fibroblasts are involved in all pathologies characterized by increased ExtraCellularMatrix synthesis, from wound healing to fibrosis. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a cytokine isolated as an hemopoietic growth factor but ...
S Montagnani   +10 more
doaj   +1 more source

Anti-Inflammatory Effects of Diospyrin on Lipopolysaccharide-Induced Inflammation Using RAW 264.7 Mouse Macrophages

open access: yesBiomedicines, 2020
Diospyrin is a bisnaphthoquinonoid medicinal compound derived from Diospyros lotus, with known anti-cancer, anti-tubercular, and anti-leishmanial activities against Leishmania donovani.
Adnan Shahidullah   +7 more
doaj   +1 more source

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