Single‐Cell Mechanical Characterization of Human Macrophages
Macrophages remodel their mechanics during differentiation toward different subtypes and drastically adapt their shapes during phagocytosis or entry to inflamed tissues.
Tom M. J. Evers +5 more
doaj +1 more source
Driving chronicity in rheumatoid arthritis: perpetuating role of myeloid cells [PDF]
Acute inflammation is a complex and tightly regulated homeostatic process that includes leukocyte migration from the vasculature into tissues to eliminate the pathogen/injury, followed by a pro-resolving response promoting tissue repair.
Achuthan +115 more
core +1 more source
Differential fMet-Leu-Phe- and Platelet-activating Factor-induced Signaling Toward Ral Activation in Primary Human Neutrophils [PDF]
We have measured the activation of the small GTPase Ral in human neutrophils after stimulation with fMet- Leu-Phe (fMLP), platelet activating factor (PAF), and granulocyte macrophage-colony stimulating factor and compared it with the activation of ...
Bos, J.L. +5 more
core +2 more sources
Application of Western Blot for detection of neutrophil apoptosis-related proteins
The aim of this study was to evaluate suitability of using Western Blot for detection of neutrophil apoptosis and neutrophil apoptosis-related proteins, respectively. Neutrophils were isolated from blood of healthy adult donors and incubated with G-CSF
Petr Sláma
doaj +1 more source
Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs [PDF]
Modulation of the immune response against tumour cells is emerging as a valuable approach for cancer treatment. Some experimental studies have shown that secretion of colony stimulating factors by cancer cells reduces their tumorigenicity and increases ...
A Suresh +23 more
core +2 more sources
The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
A Dar +47 more
core +1 more source
Desert dust exposure is associated with adverse respiratory health effects. Desert dust is a complex pollutant mixtures that includes respirable crystalline and amorphous particles, metals, and microbial constituents.
Gerrit Bredeck +3 more
doaj +1 more source
Factores de Crescimento Hematopoiético
SUMÃRIO: Os factores de crescimento hematopoiético (FCH) são glicoproteinas que regulam a proliferação e diferenciação das células sanguÃneas.
Maria De Fátima Miguel Rodrigues +3 more
doaj +1 more source
Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano +6 more
core
Evaluation of the effect of GM-CSF blocking on the phenotype and function of human monocytes [PDF]
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a multipotent cytokine that prompts the proliferation of bone marrow-derived macrophages and granulocytes.
Esmaeil, Nafiseh +3 more
core +2 more sources

