Results 1 to 10 of about 196,918 (257)

Neutralizing serum IgE upregulates CD88 and CRTH2 expression on basophils in patients with asthma [PDF]

Journal of Allergy and Clinical Immunology: Global
Background: The cross-linking of FcεRI by IgE and allergen leads to the degranulation of basophils and mast cells, which can drive allergic reactions. Neutralizing IgE with omalizumab could thus offer clinical benefits to a subset of patients with asthma.
Agnes Yang, BS, Laurie Baert, PhD, Katherine Upchurch, PhD, Matthew Wiest, PhD, Jacob Turner, PhD, HyeMee Joo, PhD, Mark Millard, MD, SangKon Oh, PhD   +7 more
doaj   +2 more sources

Low-density granulocytes and neutrophil extracellular traps in dengue, impacts of interferon alpha and cell-free DNA. [PDF]

Sci Rep
Saisorn W, Phuengmaung P, Kaewduangduen W, Bhunyakarnjanarat T, Doi K, Chancharoenthana W, Leelahavanichkul A.   +6 more
europepmc   +3 more sources

POLARIZED ACTIVATION OF HUMAN PERIPHERAL BLOOD PHAGOCYTES BY BACTERIOPHAGE–DERIVED DOUBLE-STRANDED RNA (LARIFAN) IN VITRO [PDF]

Biotechnologia Acta, 2023
Aim. This study aimed to examine the effect of Larifan on metabolic characteristics of human blood monocytes and granulocytes in vitro. Methods. Four healthy adult men aged 21-26 years were recruited to participate in the study as blood donors.
R. Dovhyi, M. Rudyk, Ye. Hurmach, T. Serhiichuk, Yu. Yumyna, A. Dvukhriadkina, K. Ostrovska, D. Pjanova, L. Skivka   +8 more
doaj   +1 more source

Genomic Organization, Splice Variants and Expression of CGMl, a CD66-related Member of the Carcinoembryonic Antigen Gene Family [PDF]

, 1993
The tumor marker carcinoembryonic antigen (CEA) belongs to a family of proteins which are composed of one immunogiobulin variable domain and a varying number of immunoglobulin constant-like domains.
Afar D. E. H., Audette M., Baniyash M., Berling B., Culic O., Elsen P., Felgner P. L., Fiddes J. C., Knapp W., Kolbinger F., Kuroki M., Kuroki M., Kuroki M., Lin S.-H., Lucas K., Margolis R. N., McCuaig K., Nap M., Neumaier M., Ng S. Y., Oikawa S., Oikawa S., Paxton R., Pelegrin A., Raskind W. H., Rojas M., Sambrook J. E., Schwarz K., Shively J. E., Skubitz K. M., Southern P. J., Thompson J. A., Thompson J. A., Turbide C., Tynan K., Watt S. M., Woodgett J. R., Zhou H.   +37 more
core   +13 more sources

Transcriptional dynamics of granulocytes in direct response to incubation with SARS‐CoV‐2

FEBS Open Bio, 2023
Severe coronavirus disease 2019 (COVID‐19) is characterized by acute respiratory distress syndrome and multiple organ dysfunction, in which the host immune response plays a pivotal role.
Daigo Nakazawa, Yohei Takeda, Masatoshi Kanda, Utano Tomaru, Haruko Ogawa, Takashi Kudo, Satoka Shiratori‐Aso, Kanako Watanabe‐Kusunoki, Yusho Ueda, Atsuko Miyoshi, Fumihiko Hattanda, Saori Nishio, Ryo Uozumi, Akihiro Ishizu, Tatsuya Atsumi   +14 more
doaj   +1 more source

Single-cell transcriptome analysis reveals a cellular immune response in freshwater dark sleeper (Odontobutis potamophila) after infection with Aeromonas veronii

Frontiers in Physiology, 2023
The bacterium Aeromonas veronii is a co-pathogenic species that can negatively impact the health of both humans and aquatic animals. In this study, we used single-cell transcriptome analysis (scRNA-seq) to investigate the effects of infection with A ...
Guoxing Liu, Guoxing Liu, Guoxing Liu, Chenxi Zhu, Xiaojian Gao, You Zheng, You Zheng, Xinhai Zhu, Hucheng Jiang, Hucheng Jiang, Wanhong Wei, Qichen Jiang, Qichen Jiang, Qichen Jiang, Xiaojun Zhang   +14 more
doaj   +1 more source

Perinatal granulopoiesis and risk of pediatric asthma

eLife, 2021
There are perinatal characteristics, such as gestational age, reproducibly associated with the risk for pediatric asthma. Identification of biologic processes influenced by these characteristics could facilitate risk stratification or new therapeutic ...
Benjamin A Turturice, Juliana Theorell, Mary Dawn Koenig, Lisa Tussing-Humphreys, Diane R Gold, Augusto A Litonjua, Emily Oken, Sheryl L Rifas-Shiman, David L Perkins, Patricia W Finn   +9 more
doaj   +1 more source

Discovery of granulocyte-lineage cells in the skin of the amphibian Xenopus laevis

FACETS, 2020
The ranavirus Frog Virus 3 (FV3) and the chytrid fungus Batrachochytrium dendrobatidis (Bd) are significant contributors to the global amphibian declines and both pathogens target the amphibian skin.
Kelsey Hauser, Milan Popovic, Amulya Yaparla, Daphne V. Koubourli, Phillip Reeves, Aashish Batheja, Rose Webb, María J. Forzán, Leon Grayfer   +8 more
doaj   +1 more source

Clinicopathological Profile of Paroxysmal Nocturnal Hemoglobinuria among Omani Patients: A Case Series

Oman Medical Journal, 2022
We aimed to estimate the nature and prevalence of paroxysmal nocturnal hemoglobinuria (PNH) among Omani patients. We performed a retrospective review of all patients who were tested for PNH by flow cytometry at the Sultan Qaboos University Hospital ...
Arwa Z. Al-Riyami, Yahya Al-Kindi, Jamal Al-Qassabi, Sahimah Al-Mamari, Naglaa Fawaz, Murtadha Al-Khabori, Mohammed Al-Huneini, Salam Al Kindi   +7 more
doaj   +1 more source

Relationship between the peroxidation of leukocytes index ratio and the improvement of postprandial metabolic stress by a functional food [PDF]

, 2015
For the first time, we investigated the relationship between postprandial dysmetabolism and the Peroxidation of Leukocytes Index Ratio (PLIR), a test that measures the resistance of leukocytes to exogenous oxidative stress and their functional capacity ...
Longhitano, Yaroslava, Manafikhi, Husseen, Palmery, Maura, Peluso, Ilaria, Reggi, Raffaella, Zanza, Christian   +5 more
core   +8 more sources