Results 31 to 40 of about 106,660 (298)

Influence of granulocytes on brain edema, intracranial pressure, and cerebrospinal fluid concentrations of lactate and protein in experimental meningitis [PDF]

, 1988
Brain water content (brain edema), intracranial pressure, and cerebrospinal fluid (CSF) concentrations of lactate and protein increased significantly during 24 h of experimental meningitis due to Streptococcus pneumoniae, but changes were similar in ...
M. G. Tauber, Borschberg, U, M. A. Sande, Täuber, MG, Tauber, M G, U. Borschberg, Sande, M A, Sande, MA   +7 more
core   +1 more source

In Vitro Differentiation of Mouse Granulocytes.

, 2016
Granulocytes are central players of the immune system and, once activated, a tightly controlled balance between effector functions and cell removal by apoptosis guarantees maximal host benefit with least possible collateral damage to healthy tissue ...
Reinhart, Ramona, Kaufmann, Thomas, Wicki, Simone, Ramona Reinhart, Simone Wicki, Thomas Kaufmann   +5 more
core   +1 more source

Neutralizing serum IgE upregulates CD88 and CRTH2 expression on basophils in patients with asthma

Journal of Allergy and Clinical Immunology: Global
Background: The cross-linking of FcεRI by IgE and allergen leads to the degranulation of basophils and mast cells, which can drive allergic reactions. Neutralizing IgE with omalizumab could thus offer clinical benefits to a subset of patients with asthma.
Agnes Yang, BS, Laurie Baert, PhD, Katherine Upchurch, PhD, Matthew Wiest, PhD, Jacob Turner, PhD, HyeMee Joo, PhD, Mark Millard, MD, SangKon Oh, PhD   +7 more
doaj   +1 more source

MST1 controls murine neutrophil homeostasis via the G-CSFR/STAT3 axis

Frontiers in Immunology, 2022
The release of neutrophils from the bone marrow into the blood circulation is essential for neutrophil homeostasis and the protection of the organism from invading microorganisms. Granulocyte colony-stimulating factor (G-CSF) plays a pivotal role in this
Sergi Masgrau-Alsina, Lou Martha Wackerbarth, Dae-sik Lim, Markus Sperandio   +3 more
doaj   +1 more source

Verification of SPIO-labeled granulocytes isolated from infected tissue.

, 2013
(A) Fraction of granulocytes isolated from infected tissue of rats treated with SPIO-labeled granulocytes. SPIO-labeled granulocytes (blue) were identified by Prussian blue staining. (B) fraction of granulocytes isolated from infected tissue of rats from
André Bleich (2201215), Silke Glage (108551), Dirk Wedekind (295505), Hassina Baraki (295503), Norman Zinne (295504), Axel Haverich (295514), Ingo Kutschka (295511), Martin Meier (295507), Hans-Juergen Hedrich (295510)   +8 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Whole-blood model reveals granulocytes as key sites of dengue virus propagation, expanding understanding of disease pathogenesis

mBio
Dengue virus (DENV) infection poses a significant global health threat, yet our understanding of its immunopathogenesis remains incomplete due to limitations of existing models.
Hansa Praneechit, Somchai Thiemmeca, Dararat Prayongkul, Kessiri Kongmanas, Dumrong Mairiang, Nuntaya Punyadee, Adisak Songjaeng, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Kanokwan Sriruksa, Yupin Suputtamongkol, Wannee Limpitikul, John P. Atkinson, Panisadee Avirutnan   +13 more
doaj   +1 more source

Neutrophil Evolution and Their Diseases in Humans

Frontiers in Immunology, 2017
Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens.
Jennifer W. Leiding, Jennifer W. Leiding
doaj   +1 more source

[Eosinophilic granulocytes-Physiology and pathophysiology].

, 2019
Eosinophilic granulocytes are a subpopulation of leucocytes and part of the innate immune cell pool. Additionally, they have homeostatic functions in different tissues.
Simon, Hans-Uwe, C. Sokollik, H.-U. Simon, Sokollik, Christiane   +3 more
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source