Verification of SPIO-labeled granulocytes isolated from infected tissue.
, 2013 (A) Fraction of granulocytes isolated from infected tissue of rats treated with SPIO-labeled granulocytes. SPIO-labeled granulocytes (blue) were identified by Prussian blue staining. (B) fraction of granulocytes isolated from infected tissue of rats from
André Bleich (2201215) +8 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
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Diagnostic values of immature granulocytes, eosinopenia and i/t ratio in detection of early onset neonatal sepsis in neonates with bacterial infection risk [PDF]
, 2014 Early Onset Neonatal Sepsis (EONS) is a significant cause of morbidity and mortality in neonates. It is difficult to establish thediagnosis of early onset neonatal sepsis and the gold standard of establishing sepsis is by microbiology method.
Puspa Wardhani, - +2 more
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Neutrophil Evolution and Their Diseases in Humans
Frontiers in Immunology, 2017 Granulocytes have been preserved and have evolved across species, developing into cells that provide one of the first lines of host defense against pathogens.
Jennifer W. Leiding, Jennifer W. Leiding
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Growth hormone on ovarian morphology of lambaris (Astyanax bimaculatus) after induced spawning
Ciência Rural: Lambari, Astyanax bimaculatus, is an oviparous, multiple-spawning fish that is reproductively active throughout the year, which makes it promising for cultivation and research.
Lucas Marcon +4 more
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Acrylamide-induced changes of granulopoiesis in porcine bone marrow
Journal of Veterinary Research, 2021 Due to the widely documented and diverse toxic effects of acrylamide, the authors decided to evaluate the impact of high and low doses of this compound on the process of granulopoiesis in porcine bone marrow.
Grzybowska Dominika, Snarska Anna
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In vitro differentiation of mouse granulocytes. Programmed Cell Death: Methods and Protocols [PDF]
, 2015 Granulocytes are central players of the immune system and, once activated, a tightly controlled balance between effector functions and cell removal by apoptosis guarantees maximal host benefit with least possible collateral damage to healthy tissue ...
Kaufmann, Thomas +2 more
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Images of immunologically activated granulocytes and encapsulation.
, 2014 (A and B) granulocytes changed their shape rapidly and generated large lobopodia-like, fan-like, or amoeba-like structures (indicated by white arrow). The highly polymorphic glittering vacuoles of variable size and round or irregular shape were closely ...
Saeyoull Cho (607394) +2 more
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