Results 51 to 60 of about 106,660 (298)

Key Signature Genes of Early Terminal Granulocytic Differentiation Distinguish Sepsis From Systemic Inflammatory Response Syndrome on Intensive Care Unit Admission

Frontiers in Immunology, 2022
Infection can induce granulopoiesis. This process potentially contributes to blood gene classifiers of sepsis in systemic inflammatory response syndrome (SIRS) patients.
Sonia Y. Velásquez, Anna Coulibaly, Carsten Sticht, Jutta Schulte, Bianka Hahn, Timo Sturm, Roman Schefzik, Manfred Thiel, Manfred Thiel, Holger A. Lindner, Holger A. Lindner   +10 more
doaj   +1 more source

Images of immunologically activated granulocytes and encapsulation.

, 2014
(A and B) granulocytes changed their shape rapidly and generated large lobopodia-like, fan-like, or amoeba-like structures (indicated by white arrow). The highly polymorphic glittering vacuoles of variable size and round or irregular shape were closely ...
Saeyoull Cho (607394), Hyojung Kwon (607392), Kyeongrin Bang (607393)   +2 more
core   +1 more source

Destination Airway : Tracking Granulocytes in Asthma

, 2014
Destination Airway : Tracking Granulocytes in ...
Christopher Edward Brightling (7632470)
core   +2 more sources

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Impact of exposure time, particle size and uptake pathway on silver nanoparticle effects on circulating immune cells in mytilus galloprovincialis

Journal of Immunotoxicology, 2017
Nanomaterials have increasingly emerged as potential pollutants to aquatic organisms. Nanomaterials are known to be taken up by hemocytes of marine invertebrates including Mytilus galloprovincialis.
Younes Bouallegui, Ridha Ben Younes, Faten Turki, Ridha Oueslati   +3 more
doaj   +1 more source

Decreased expression of FcγRIII mRNA in leukemic granulocytes

, 1992
Morphologically mature granulocytes from patients with chronic myeloid leukemia show significant impairment in their ability to internalize aggregated IgG, a ligand that is rapidly phagocytosed by normal human granulocytes.
Suresh Advani, Monteiro, Joanita, Surekha Zingde, Gothoskar, Balwant, Balwant Gothoskar, Zingde, Surekha, Advani, Suresh, Joanita Monteiro   +7 more
core   +1 more source

Diabetes mellitus impairs circulating proangiogenic granulocytes

, 2020
Aims/hypothesis: Cardiovascular risk in diabetes is at least in part attributable to defective angiogenesis. Since diabetes negatively affects blood cells involved in angiogenesis, we herein evaluated whether diabetes impairs proangiogenic granulocytes ...
Bonora B. M., Fadini G. P., Avogaro A., Albiero M., Menegazzo L., Cappellari R., D'Anna M.   +6 more
core   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function

Frontiers in Immunology, 2018
GM-CSF promotes myeloid differentiation of cultured bone marrow cells into cells of the granulocytic and monocytic lineage; the latter can further differentiate into monocytes/macrophages and dendritic cells.
Li Sun, Jai Rautela, Jai Rautela, Rebecca B. Delconte, Rebecca B. Delconte, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes, Emma M. Carrington, Emma M. Carrington, Robyn L. Schenk, Robyn L. Schenk, Marco J. Herold, Marco J. Herold, Nicholas D. Huntington, Nicholas D. Huntington, Andrew M. Lew, Andrew M. Lew, Andrew M. Lew, Yuekang Xu, Yifan Zhan, Yifan Zhan, Yifan Zhan   +21 more
doaj   +1 more source

Cryopreservation of human granulocytes: study of granulocyte function and ultrastructure [PDF]

Blood, 1980
Abstract Human granulocytes can be cryopreserved with dimethyl sulfoxide (DMSO) at--80 degrees C. However, the percent recovery of functional cells has been unsatisfactory to date. Throughout this study we have been able to prepare relatively pure granulocytes approximately equal to 85%), cryopreserve them with 5%--10% DMSO with and ...
P, Boonlayangoor, M, Telischi, S, Boonlayangoor, T F, Sinclair, E W, Millhouse   +4 more
openaire   +3 more sources