Results 71 to 80 of about 106,660 (298)

Avaliação da inflamação com base na liberação de radicais oxidantes por granulócitos na asma crônica não-controlada Assessment of inflammation based on the release of oxygen radicals by granulocytes in chronic uncontrolled asthma

Jornal de Pediatria, 2009
OBJETIVO: Avaliar a liberação espontânea de ânion superóxido por granulócitos de sangue periférico de pacientes com asma crônica não-controlada antes e após corticoterapia e de indivíduos sadios.
Cristina F. Sartorelli, Jussara Rehder, Antonio Condino Neto, Maria Marluce S. Vilela   +3 more
doaj   +1 more source

Functional properties of granulocytes after thermal injury

, 2012
Thermal injury, as well as other forms of severe trauma, induces simultaneous hyper- and anti-inflammatory response. While data about decreased number and responsiveness of T lymphocytes are largely consistent, reports concerning granulocytes following ...
Biljana Bozic, Draskovic-Pavlovic, Biljana, Vucevic, Dragana, Dragana Vucevic, Ivana Majstorovic, Majstorovic, Ivana, Božić, Biljana, Colic, Miodrag, Miodrag Colic, Biljana Draskovic-Pavlovic   +9 more
core   +1 more source

Tumor‐Intrinsic ARHGEF3 Enhances Antitumor Immunity by Promoting T‐Cell Infiltration and Limiting Myeloid Cell‐Mediated Immunosuppression

Advanced Science, EarlyView.
ARHGEF3 is broadly downregulated across human cancers and correlates with patient prognosis. Tumor‐intrinsic ARHGEF3 activates the RHOA–ROCK–PTEN cascade to inhibit AKT signaling, thereby promoting chemokine‐driven T‐cell infiltration and relieving lipid‐mediated myeloid immunosuppression.
Yue Li, Lan Wang, Zihao Zhang, Chunmei Qian, Ning Li, Wei Huang, Qian Ba, Xiaojian Liu, Mayu Sun   +8 more
wiley   +1 more source

Promotion of Tumor Invasion by Cooperation of Granulocytes and Macrophages Activated by Anti-tumor Antibodies

Neoplasia: An International Journal for Oncology Research, 1999
We investigated the potential role of anti-tumor antibodies and tumor antigens in the formation of immune complexes which promote matrix degradation and angiogenesis.
Emilio Barbera-Guillem, Kenneth F. May, Jr., Julie K. Nyhus, M. Bud Nelson   +3 more
doaj   +1 more source

Transcriptomic Evidence Reveals the Molecular Basis for Functional Differentiation of Hemocytes in a Marine Invertebrate, Crassostrea gigas

Frontiers in Immunology, 2020
Hemocytes play unequivocally central roles in host immune defense of bivalve mollusks, though the exact mechanisms underlying their functional differentiation are only partially understood.
Fan Mao, Fan Mao, Fan Mao, Nai-Kei Wong, Yue Lin, Yue Lin, Yue Lin, Xiangyu Zhang, Xiangyu Zhang, Xiangyu Zhang, Kunna Liu, Kunna Liu, Kunna Liu, Minwei Huang, Minwei Huang, Minwei Huang, Duo Xu, Duo Xu, Duo Xu, Zhiming Xiang, Zhiming Xiang, Zhiming Xiang, Jun Li, Jun Li, Jun Li, Yang Zhang, Yang Zhang, Yang Zhang, Ziniu Yu, Ziniu Yu, Ziniu Yu   +30 more
doaj   +1 more source

Complete internalization of large foreign particles by granulocytes.

, 2014
Hemocytes (average size 20.1 µm, n = 30) from the Stag Beetle Lucanus maculifemoratus (Coleoptera: Lucanidae) were injected into the hemocoel. At 12 h post injection, highly polymorphic glittering vacuoles were generated in the granulocytes. (A through C)
Saeyoull Cho (607394), Hyojung Kwon (607392), Kyeongrin Bang (607393)   +2 more
core   +1 more source

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Differential white blood cell counts in apparently healthy Eritrean blood donors at the National Blood Transfusion Center, Asmara, Eritrea

Population Medicine, 2020
Introduction To our knowledge, no study has been conducted on white blood cell counts in healthy Eritrean blood donors. Therefore, this study will help to establish the reference ranges of white blood cell (WBC) counts in Eritrean people and to correlate
Faris M. Abdon, Elias T. Adgoy, Nahom Y. Berhane, Senet A. Ibrahim, Adil K. H. Khalil, Yemane Seyoum, Osama S. Abbadi   +6 more
doaj   +1 more source

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Changes in the exposure of CD11b on the surface of granulocytes, after activation of Toll-like receptors in children with recurrent infections

Біологічні студії, 2016
The effect of activation of Toll-like receptors (TLR) on presentation of CD11b adhesion molecule at the granulocytes surface in children of different age with recurrent infections was investigated.
D. V. Osypchuk, O. V. Rabosh
doaj   +1 more source