Results 51 to 60 of about 187,796 (337)

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function

Frontiers in Immunology, 2018
GM-CSF promotes myeloid differentiation of cultured bone marrow cells into cells of the granulocytic and monocytic lineage; the latter can further differentiate into monocytes/macrophages and dendritic cells.
Li Sun, Jai Rautela, Jai Rautela, Rebecca B. Delconte, Rebecca B. Delconte, Fernando Souza-Fonseca-Guimaraes, Fernando Souza-Fonseca-Guimaraes, Emma M. Carrington, Emma M. Carrington, Robyn L. Schenk, Robyn L. Schenk, Marco J. Herold, Marco J. Herold, Nicholas D. Huntington, Nicholas D. Huntington, Andrew M. Lew, Andrew M. Lew, Andrew M. Lew, Yuekang Xu, Yifan Zhan, Yifan Zhan, Yifan Zhan   +21 more
doaj   +1 more source

Transcriptomic Evidence Reveals the Molecular Basis for Functional Differentiation of Hemocytes in a Marine Invertebrate, Crassostrea gigas

Frontiers in Immunology, 2020
Hemocytes play unequivocally central roles in host immune defense of bivalve mollusks, though the exact mechanisms underlying their functional differentiation are only partially understood.
Fan Mao, Fan Mao, Fan Mao, Nai-Kei Wong, Yue Lin, Yue Lin, Yue Lin, Xiangyu Zhang, Xiangyu Zhang, Xiangyu Zhang, Kunna Liu, Kunna Liu, Kunna Liu, Minwei Huang, Minwei Huang, Minwei Huang, Duo Xu, Duo Xu, Duo Xu, Zhiming Xiang, Zhiming Xiang, Zhiming Xiang, Jun Li, Jun Li, Jun Li, Yang Zhang, Yang Zhang, Yang Zhang, Ziniu Yu, Ziniu Yu, Ziniu Yu   +30 more
doaj   +1 more source

Aspects of leucocyte and fat filtration during cardiac surgery [PDF]

, 2005
Na een hartoperatie treden vaak door het hele lichaam ontstekingsreacties op. Door het bloed tijdens de operatie te filteren, lopen patiënten minder risico op beschadigingen in longen, hart en hersenen, ontdekte Hans de Vries.
Vries, Adrianus Johannes de,
core   +3 more sources

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings

Advanced Therapeutics, EarlyView.
Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy, Kubra Sener, M. Burcu Külahci, K. Barbaros Balabanli, Şule Coşkun Cevher   +4 more
wiley   +1 more source

Detection of Functional Overreaching in Endurance Athletes Using Proteomics

Proteomes, 2018
No reliable biomarkers exist to identify athletes in various training states including functional overreaching (FOR), non-functional overreaching (NFOR), and overtraining syndrome (OTS).
David C. Nieman, Arnoud J. Groen, Artyom Pugachev, Gianmarco Vacca   +3 more
doaj   +1 more source

Leukapheresis and Granulocyte Transfusion

CRC Critical Reviews in Clinical Laboratory Sciences, 1979
Granulocytes for transfusion can now be obtained from normal donors by one of four techniques that involve either centrifugation or reversible adhesion of granulocytes to nylon fibers. The leukapheresis process appears to be safe for donors and standards for the selection and care of donors are being formulated.
Jeffrey McCullough, Donald J. Higby
openaire   +3 more sources

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

Advanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng, Xuegang Wang, Mingjun Zhong, Jia Geng, Wenjian Li, Kanglu Pei, Jing Wang, Lanchen Wang, Yu Lu, Jing Cheng, Fengxiao Bu, Huijun Yuan   +11 more
wiley   +1 more source

The impact of pre-analytical treatment and sorting on human neutrophil function

Veterinární Medicína, 2014
This study was designed to test the hypothesis that pre-analytical treatment of relatively fragile cells is more important for their viability and function than shear forces and decompression shocks on a flow cytometric sorter.
L. Hromadkova, L. Zarybnicka, J. Vavrova, Z. Bilkova, Z. Sinkorova   +4 more
doaj   +1 more source