Results 31 to 40 of about 953 (126)

Amebicidal and Antiadhesion Activities of Knema retusa Extract Against Acanthamoeba triangularis T4 Genotype on Contact Lenses and Modeling Simulation of Its Main Compound, E2N, Against Acanthamoeba Beta‐Tubulin

Scientifica, Volume 2025, Issue 1, 2025.
Medicinal plants have been used as alternative agents for the treatment of infections. This study aimed to investigate bioactivities of medicinal plant extracts including Knema retusa extract (Kre) against Acanthamoeba triangularis T4 in vitro and in silico. Anti‐Acanthamoeba activities of 44 extracts from 5 plant species were determined.
Watcharapong Mitsuwan, Imran Sama-ae, Suthinee Sangkanu, Dhrubo Ahmed Khan, Partha Biswas, Md. Nazmul Hasan, Julalak Chuprom, Tajudeen O. Jimoh, Christophe Wiart, Masyitah Binti Zulkipli, Nor Hayati Abdullah, Maria de Lourdes Pereira, Sonia M. Rodrigues Oliveira, Shanmuga Sundar Saravanabhavan, Polrat Wilairatana, Tooba Mahboob, Veeranoot Nissapatorn, Sukhamoy Gorai   +17 more
wiley   +1 more source

Modelling dynamics between free‐living amoebae and bacteria

Environmental Microbiology, Volume 26, Issue 5, May 2024.
This review scrutinizes mathematical models designed to simulate the interactions between free‐living amoebae and bacteria. Identified gaps encompass (1) the necessity to tackle complexities such as spatial heterogeneity and population diversity; and (2) the essential understanding of the system.
Marwa Ali, Christopher A. Rice, Andrew W. Byrne, Philip E. Paré, Wendy Beauvais   +4 more
wiley   +1 more source

Glucose metabolism in the pathogenic free‐living amoebae: Tempting targets for treatment development

Chemical Biology &Drug Design, Volume 103, Issue 1, January 2024.
Enzymes involved in glucose metabolism may be promising therapeutic targets for drug development against the pathogenic free‐living amoebae. Details about the enzyme sequence and structural properties make a compelling case for designing small molecule inhibitors that are specific to the amoebae and would not affect the host enzyme.AbstractPathogenic ...
Jillian E. Milanes, Samuel Kwain, Allyson Drawdy, Laura Dodson, Matthew T. Monaghan, Christopher A. Rice, Brian N. Dominy, Daniel C. Whitehead, James C. Morris   +8 more
wiley   +1 more source

Granulomatous amoebic encephalitis caused by Balamuthia mandrillaris.

Neurologia medico-chirurgica, 2013
A 51-year-old immunocompetent Japanese woman presented with a rare case of granulomatous amoebic encephalitis (GAE) caused by Balamuthia mandrillaris. She was brought to our hospital with epilepsy. Magnetic resonance imaging of the brain revealed a homogeneously enhanced solitary mass in the left frontal lobe.
Kouji, Yamasaki, Tetsuaki, Sugimoto, Munetomo, Futami, Takuzo, Moriyama, Hisao, Uehara, Hideo, Takeshima, Sayaka, Moriguchi, Kousuke, Marutsuka, Yujiro, Asada   +8 more
openaire   +1 more source

Granulomatous Amoebic Encephalitis Caused by Acanthamoeba Amoebae of Genotype T2 in a Human Immunodeficiency Virus-Negative Patient [PDF]

Journal of Clinical Microbiology, 2008
ABSTRACT Acanthamoeba amoebae of genotype T2 were identified as the causative agent of Acanthamoeba skin lesions and granulomatous amoebic encephalitis (GAE) in a human immunodeficiency virus-negative patient with underlying tuberculosis.
Julia, Walochnik, Alexander, Aichelburg, Ojan, Assadian, Andrea, Steuer, Govinda, Visvesvara, Norbert, Vetter, Horst, Aspöck   +6 more
openaire   +2 more sources

Morphological Characterization and Genotyping of Acanthamoeba Isolates From Oral and Nasal Samples of Cancer Patients in Kashan, Iran

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2024, Issue 1, 2024.
Background: Acanthamoeba​ species are recognized as the most prevalent free‐living amoebae (FLA). They can cause granulomatous amebic encephalitis (GAE) and pulmonary and ocular infections. The present study aimed to isolate and identify Acanthamoeba genotypes in cancer patients referred to Kashan’s hospitals in Central Iran.
Sima Rasti, Tayebeh Taghipour, Mahdi Delavari, Hossein Hooshyar, Gholam Abbas Moosavi, Mohsen Arbabi, Hemant Joshi   +6 more
wiley   +1 more source

Quercetin as a Promising Antiprotozoan Phytochemical: Current Knowledge and Future Research Avenues

BioMed Research International, Volume 2024, Issue 1, 2024.
Despite tremendous advances in the prevention and treatment of infectious diseases, only few antiparasitic drugs have been developed to date. Protozoan infections such as malaria, leishmaniasis, and trypanosomiasis continue to exact an enormous toll on public health worldwide, underscoring the need to discover novel antiprotozoan drugs. Recently, there
Hamed Memariani, Mojtaba Memariani, Abdolmajid Ghasemian, Rahul Shivahare   +3 more
wiley   +1 more source

Granulomatous amoebic encephalitis: ghost response of an immunocompromised host?

Journal of Medical Microbiology, 2014
Naegleria fowleri, Acanthamoeba and Balamuthia mandrillaris spp. are known to cause fatal amoebic encephalitis. Here, I attempt to draw attention to these cases, which are reported as ‘granulomatous amoebic encephalitis’ (GAE), and their occurrence in immunocompromised individuals and patients with AIDS.
openaire   +2 more sources

Molecular Docking Study of Heterocyclic Compounds for Antifungal Activity Against Granulomatous Amoebic Encephalitis

Journal of Pharmaceutical Research
Our study identified seven unique heterocyclic compounds: 2-(m Tolylthio) Chalcone, chitosan oligosaccharide, and 2-hydroxy chalcone. Six-chloropyridine, 4-naphthoquinone, Thiobenzimidazole, 2-thiobenzoxazole, 6-carboxylic acid ethyl ester, and Anthrimide are probable choices that may be found in a chemical database.
Thomas Kurian, Rani Sebastian
openaire   +2 more sources

Amoebic granulomatous encephalitis in an immunocompetent patient

, 2016
Granulomatous amoebic encephalitis is an infrequent clinical entity, usually present in immunocompromised persons, where the few cases reported in the literature are due to infections by free-living amoebas present throughout the world, standing out as the most common agents, the Acanthamoeba sp. and Balamuthia mandrillaris.
Matos, Roberto, Ruiz, Jenny, Casanova, Leonardo, Gonzalez, Gustavo   +3 more
openaire   +1 more source