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Chronic granulomatous disease [PDF]

Indian Dermatology Online Journal, 2015
Chronic Granulomatous Disease (CGD) is an inherited immunodeficiency disorder characterized by defective functioning of NADPH oxidase enzyme in the phagocytes.
Kikkeri Narayanasetty Naveen, Adagadde Venkataramana Pradeep   +1 more
doaj   +8 more sources

Non Indigenous Rhinoscleroma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Rhinoscleroma (RS) is a granulomatous illness of the upper respiratory tract caused by Klebsiella rhinoscleromatis. It is a rare, chronic, granulomatous disease.
Prabakaran Somu, RB Namasivaya Navin, S Rajasekaran, Raghvi Anand   +3 more
doaj   +1 more source

Second Report of Chronic Granulomatous Disease in Jordan: Clinical and Genetic Description of 31 Patients From 21 Different Families, Including Families From Lybia and Iraq

Frontiers in Immunology, 2021
Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri, Faris Ghalib Bakri, Michelle Mollin, Sylvain Beaumel, Bénédicte Vigne, Nathalie Roux-Buisson, Nathalie Roux-Buisson, Adel Mohammed Al-Wahadneh, Raed Mohammed Alzyoud, Wail Ahmad Hayajneh, Ammar Khaled Daoud, Mohammed Elian Abu Shukair, Mansour Fuad Karadshe, Mahmoud Mohammad Sarhan, Jamal Ahmad Wadi Al-Ramahi, Julien Fauré, Julien Fauré, John Rendu, John Rendu, Marie Jose Stasia, Marie Jose Stasia   +20 more
doaj   +1 more source

A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?

Dermatology Reports, 2022
We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco, Claudio Feliciani, Maria Beatrice de Felici del Giudice   +2 more
doaj   +1 more source

What Works When Treating Granulomatous Disease in Genetically Undefined CVID? A Systematic Review

Frontiers in Immunology, 2020
BackgroundGranulomatous disease is reported in at least 8–20% of patients with common variable immunodeficiency (CVID). Granulomatous disease mainly affects the lungs, and is associated with significantly higher morbidity and mortality.
Astrid C. van Stigt, Astrid C. van Stigt, Astrid C. van Stigt, Willem A. Dik, Willem A. Dik, Lieke S. J. Kamphuis, Lieke S. J. Kamphuis, Bas M. Smits, Joris M. van Montfrans, P. Martin van Hagen, P. Martin van Hagen, P. Martin van Hagen, Virgil A. S. H. Dalm, Virgil A. S. H. Dalm, Virgil A. S. H. Dalm, Hanna IJspeert, Hanna IJspeert   +16 more
doaj   +1 more source

Etiology of granulomatous inflammation: A retrospective study of 174 children in a tertiary care center

Asian Pacific Journal of Tropical Medicine, 2022
Objective: To investigate granulomatous inflammation etiology based on clinical history and ancillary tests. Methods: Children aged
Ummühan Cay, Derya Alabaz, Özlem Özgür Gündeşlioğlu, Aysun Hatice Uguz, Hande Yanar   +4 more
doaj   +1 more source

Vaping-related pulmonary granulomatous disease

Respiratory Medicine Case Reports, 2020
The use of electronic cigarettes, or “vaping,” has garnered significant popularity and attention in recent years. Its pulmonary and systemic effects have yet to be fully studied and quantified, and recent reports of vaping-related illnesses and deaths ...
Charlie Lin, Valeria Arrossi, Ruchi Yadav, Humberto Choi   +3 more
doaj   +1 more source

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]

, 2013
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi, A Fortin, A Kahnert, A Mantovani, AM Becker, Anna Giagu, Antonio Giovanni Anfossi, CY Chen, DM Carragher, DM Lowe, E Corsiero, Elisabetta Antuofermo, F Mattei, Fabrizio Mattei, Filippo Belardelli, G Delogu, G Schiavoni, Giovanna Schiavoni, Giovanni Delogu, Giovanni Fadda, HP Gideon, Ivana Palucci, JF Marquis, JG Egen, JL Flynn, K Turcotte, K Turcotte, KB Urdahl, KK Huynh, L Gabriele, L Guglani, L Ramakrishnan, Laura Abalsamo, Lucia Gabriele, M Behr, M Munder, M Sali, Massimo Sanchez, MC Tsai, ME El Shikh, Michela Sali, MP Berry, NA Giese, Olivier Neyrolles, P Tailor, PJ Maglione, RL Hunter, S Hambleton, S Kunnath-Velayudhan, SA Luther, SS Kashino, Stefano Rocca, SY Foo, T Holtschke, T Ulrichs, TA Day, TD Randall, X Zhou, Y Yoshikai   +58 more
core   +15 more sources

Improvement of granulomatous skin conditions with tofacitinib in three patients: A case report

SAGE Open Medical Case Reports, 2021
Granulomatous skin conditions are poorly understood inflammatory skin diseases consisting predominantly of macrophages. Granuloma annulare (GA) is the most common granulomatous skin disease and the generalized variant is particularly difficult to treat ...
Meghan L McPhie, William C Swales, Melinda J Gooderham   +2 more
doaj   +1 more source

In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsy specimens of intestinal tuberculosis and Crohn disease [PDF]

, 2008
Tuberculosis and Crohn disease are granulomatous disorders affecting the intestinal tract with similar clinical manifestations and pathologic features.
Donoghue, HD, Peter, S, Pulimood, AB, Rook, GWA   +3 more
core   +1 more source