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Chronic Granulomatous Disease [PDF]

Journal of Clinical and Diagnostic Research, 2015
Chronic Granulomatous Disease (CGD) is an inherited immunodeficiency disorder characterized by defective functioning of NADPH oxidase enzyme in the phagocytes.
Shreya Agarwal
doaj   +8 more sources

Chronic granulomatous disease [PDF]

British Medical Bulletin, 2016
Chronic granulomatous disease is a clinical condition that stems from inactivating mutations in NOX2 and its auxiliary proteins. Together, these proteins form the phagocyte NADPH oxidase enzyme that generates superoxide. Superoxide (O2ċ-) and its reduced product hydrogen peroxide (H2O2) give rise to several additional reactive oxygen species (ROS ...
Dirk Roos
semanticscholar   +9 more sources

Inherited p40phox deficiency differs from classic chronic granulomatous disease [PDF]

Journal of Clinical Investigation, 2018
Biallelic loss-of-function (LOF) mutations of the NCF4 gene, encoding the p40phox subunit of the phagocyte NADPH oxidase, have been described in only 1 patient. We report on 24 p40phox-deficient patients from 12 additional families in 8 countries.
Dinauer, Mary C, et al,
core   +3 more sources

Aspergillosis in Chronic Granulomatous Disease

Journal of Fungi, 2016
Patients with chronic granulomatous disease (CGD) have the highest life-time incidence of invasive aspergillosis and despite the availability of antifungal prophylaxis, infections by Aspergillus species remain the single most common infectious cause of ...
Jill King, Stefanie S. V. Henriet, Adilia Warris   +2 more
doaj   +2 more sources

Diagnosing granulomatous disease during appendectomy

Clinical Case Reports, 2021
Difficulties during surgery are uncommon situations in appendectomy. For granulomatous appendicitis, literature is insufficient about surgical findings. The procedure of a 17‐year‐old male patient was a struggle due to adhesions.
Atilla Şenaylı
doaj   +2 more sources

Report of 2 Cases of Chronic Granulomatous Disease in Adults

پزشکی بالینی ابن سینا, 2007
Introduction: Chronic granulomatous disease (CGD) is an inherited disorder of phagocyte function . The defect of intracellular killing in phagocytes is the cause of recurrent pyogenic infection of patients .
Mahdi Eskandarlou, Seyyed Hamid Hashemi, Mehrdad Hajiloie, Arash Dehghan, Mohammad Sadegh Saba, Hamid Shahnazari   +5 more
doaj   +1 more source

Non Indigenous Rhinoscleroma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Rhinoscleroma (RS) is a granulomatous illness of the upper respiratory tract caused by Klebsiella rhinoscleromatis. It is a rare, chronic, granulomatous disease.
Prabakaran Somu, RB Namasivaya Navin, S Rajasekaran, Raghvi Anand   +3 more
doaj   +1 more source

Second Report of Chronic Granulomatous Disease in Jordan: Clinical and Genetic Description of 31 Patients From 21 Different Families, Including Families From Lybia and Iraq

Frontiers in Immunology, 2021
Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) encoding the superoxide-producing nicotinamide adenine dinucleotide phosphate (NADPH)
Faris Ghalib Bakri, Faris Ghalib Bakri, Michelle Mollin, Sylvain Beaumel, Bénédicte Vigne, Nathalie Roux-Buisson, Nathalie Roux-Buisson, Adel Mohammed Al-Wahadneh, Raed Mohammed Alzyoud, Wail Ahmad Hayajneh, Ammar Khaled Daoud, Mohammed Elian Abu Shukair, Mansour Fuad Karadshe, Mahmoud Mohammad Sarhan, Jamal Ahmad Wadi Al-Ramahi, Julien Fauré, Julien Fauré, John Rendu, John Rendu, Marie Jose Stasia, Marie Jose Stasia   +20 more
doaj   +1 more source

A case of chronic granulomatous disease and acne: is isotretinoin a safe treatment?

Dermatology Reports, 2022
We report the case of a patient with chronic granulomatous disease and acne treated with isotretinoin, who developed a diffuse staphylococcal skin infection during the therapy. Chronic granulomatous disease is a rare genetic disorder characterized by an
Marco Brusasco, Claudio Feliciani, Maria Beatrice de Felici del Giudice   +2 more
doaj   +1 more source

What Works When Treating Granulomatous Disease in Genetically Undefined CVID? A Systematic Review

Frontiers in Immunology, 2020
BackgroundGranulomatous disease is reported in at least 8–20% of patients with common variable immunodeficiency (CVID). Granulomatous disease mainly affects the lungs, and is associated with significantly higher morbidity and mortality.
Astrid C. van Stigt, Astrid C. van Stigt, Astrid C. van Stigt, Willem A. Dik, Willem A. Dik, Lieke S. J. Kamphuis, Lieke S. J. Kamphuis, Bas M. Smits, Joris M. van Montfrans, P. Martin van Hagen, P. Martin van Hagen, P. Martin van Hagen, Virgil A. S. H. Dalm, Virgil A. S. H. Dalm, Virgil A. S. H. Dalm, Hanna IJspeert, Hanna IJspeert   +16 more
doaj   +1 more source