Vaping-related pulmonary granulomatous disease
The use of electronic cigarettes, or “vaping,” has garnered significant popularity and attention in recent years. Its pulmonary and systemic effects have yet to be fully studied and quantified, and recent reports of vaping-related illnesses and deaths ...
Charlie Lin+3 more
doaj
Bacillus Calmette-Guerin (BCG) is considered the most effective adjunctive treatment available to treat superficial bladder carcinoma. Although BCG is well tolerated by most patients, it may be associated with adverse effects.
Suresh Bhat+2 more
doaj +1 more source
The role of mutation rate variation and genetic diversity in the architecture of human disease [PDF]
We have investigated the role that the mutation rate and the structure of genetic variation at a locus play in determining whether a gene is involved in disease. We predict that the mutation rate and its genetic diversity should be higher in genes associated with disease, unless all genes that could cause disease have already been identified ...
arxiv +1 more source
Granulomatous mastitis: An underdiagnosed inflammatory disease afflicting minority women
Granulomatous mastitis (GM) is an underdiagnosed and understudied benign inflammatory disease of the breast whose accurate diagnosis is confounded by mimicry of other breast pathologies (infectious mastitis and abscess, malignancy) and limited clinician ...
Daniel R. Bacon, BS+2 more
doaj
Post-mortem culture of Balamuthia mandrillaris from the brain and cerebrospinal fluid of a case of granulomatous amoebic meningoencephalitis, using human brain microvascular endothelial cells [PDF]
The first isolation in the UK of Balamuthia mandrillaris amoebae from a fatal case of granulomatous amoebic meningoencephalitis is reported. Using primary cultures of human brain microvascular endothelial cells (HBMECs), amoebae were isolated from the ...
Alsam+32 more
core +1 more source
Unveiling new disease, pathway, and gene associations via multi-scale neural networks [PDF]
Diseases involve complex processes and modifications to the cellular machinery. The gene expression profile of the affected cells contains characteristic patterns linked to a disease. Hence, biological knowledge pertaining to a disease can be derived from a patient cell's profile, improving our diagnosis ability, as well as our grasp of disease risks ...
arxiv +1 more source
Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal+11 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
68Ga‐nitroimidazole PET/CT imaging of hypoxia in tuberculosis: A case series
There is increasing application of PET/CT imaging in infectious diseases such as tuberculosis. Imaging potential stressors such as hypoxia, using a novel Ga‐68 labelled hypoxia seeking agent, has the potential to identify patients who may benefit from individualised treatment strategies.
Philippa L Bresser+3 more
wiley +1 more source
Gender and uveitis in patients with multiple sclerosis. [PDF]
Multiple sclerosis (MS), a demyelinating disease of the central nervous system, is more commonly seen in women. It has been associated with both anterior and intermediate uveitis as well as retinal vasculitis.
Goldstein, Debra A, Gordon, Lynn K
core +3 more sources