Results 91 to 100 of about 35,653 (216)

Malignant Granulosa-Cell Tumour [PDF]

Proceedings of the Royal Society of Medicine, 1946
openaire   +2 more sources

Anti‐Müllerian Hormone and Metabolic–Hormonal Profiles in Women With and Without Polycystic Ovary Syndrome: A Population‐Based Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In this population‐based study of 883 women, AMH declined less with age in women with PCOS than in healthy women. Higher AMH may protect older healthy women from T2DM but indicates elevated metabolic risk in younger women with PCOS, supporting its role as a life‐course biomarker for metabolic risk stratification.
Fahimeh Ramezani Tehrani, Maryam Mousavi, Marzieh Saei Ghare Naz, Maryam Farahmand, Masoumeh Jorjani, Fatemeh Mahboobifard   +5 more
wiley   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid, Maria Maqsood, Nimrah Ashraf, Farzeen Asghar, Nauman Khalid   +4 more
wiley   +1 more source

Long non-coding RNA NEAT1 promotes ovarian granulosa cell proliferation and cell cycle progression via the miR-29a-3p/IGF1 axis

Journal of Ovarian Research
Background Granulosa cell proliferation and survival are essential for normal ovarian function and follicular development. Long non-coding RNAs (lncRNAs) have emerged as important regulators of cell proliferation and differentiation.
Lina He, Jie Lin, Zhengwen Qin, Qing Xu, Li Hao, Yanhong Fu, Xu Ran, Wei Chen   +7 more
doaj   +1 more source

Graded Levels of Dietary Valine in Protein‐Restricted Diets: Effects on Reproductive Performance and Tissue Morphology in Laying Japanese Quail

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Dietary supplementation of 0.95% valine in protein‐restricted diets optimizes reproductive performance, egg quality, and ovarian follicular development in laying Japanese quail. Higher levels do not provide additional benefits and may increase hepatic metabolic demand, highlighting the importance of precise amino acid formulation in low‐protein feeding
Morteza Pashaei Jalal, Alireza Alizadeh Moghadam Mosouleh, Seyed Davood Sharifi, Abouzar Najafi   +3 more
wiley   +1 more source

Modification of the Transcription Factor FOXL2 at Serines 101 and 107 Disables DNA Binding, Leads to Nucleolar Relocalization, and Rewires Granulosa‐Cell Programs

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
PKC‐mediated phosphorylation of FOXL2 weakens DNA binding, alters subnuclear localization and protein interactions, and reshapes FOXL2‐dependent transcriptional programs in granulosa cells, supporting a reversible mechanism that modulates FOXL2 activity through phosphorylation of its DNA‐binding domain. ABSTRACT FOXL2 is a forkhead transcription factor
Ludovic Mousseron, Despoina Chousianiti, Francis Poulat, Bérangère Legois, Reiner A. Veitia, Anne‐Laure Todeschini   +5 more
wiley   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, Volume 13, Issue 43, 3 August 2026.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

Human mesenchymal stem cells derived exosomes improve ovarian function in chemotherapy-induced premature ovarian insufficiency mice by inhibiting ferroptosis through Nrf2/GPX4 pathway

Journal of Ovarian Research
Background Chemotherapy exposure has become a main cause of premature ovarian insufficiency (POI). This study aimed to evaluate the role and molecular mechanism of human umbilical cord mesenchymal stem cell-derived exosomes (hUMSC-Exos) in ovarian ...
Yuan Zhou, Jinfa Huang, Lingling Zeng, Qian Yang, Fangjuan Bai, Qiqing Mai, Kaixian Deng   +6 more
doaj   +1 more source

Follicle Size Regulates Cytoplasmic Maturation, Lipid Content, and Embryo Cryosurvival in Bovine Oocytes Matured In‐Vitro

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
Follicle size modulates bovine oocyte cytoplasmic maturation during IVM. Oocytes from larger follicles exhibit reduced lipid accumulation, fewer transzonal projections, distinct cumulus cell metabolic signaling, and greater embryo cryosurvival, indicating improved cytoplasmic maturation and lipid regulation despite similar developmental rates ...
Briza Castro, Paula Rodriguez‐Villamil, M. Sofia Ortega   +2 more
wiley   +1 more source