Results 81 to 90 of about 31,762 (231)

TGFβ controls ovarian cancer cell proliferation [PDF]

, 2018
There have been no major improvements in the overall survival of ovarian cancer patients in recent decades. Even though more accurate surgery and more effective treatments are available, the mortality rate remains high.
Alsina Sanchís, Elisenda, Figueras i Amat, Agnès, Gil-Martín, Marta, Lahiguera, Álvaro, Martí, Lola, Matias-Guiu, Xavier, Pardo, Beatriz, Piulats, Josep M., Ponce i Sebastià, Jordi, Vidal-Bel, August, Villanueva Garatachea, Alberto, Viñals Canals, Francesc   +11 more
core   +1 more source

Long‐term outcome in a dog with a unilateral ovarian granulosa cell tumour with a concurrent non‐neoplastic abdominal effusion following ovariohysterectomy

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract An 8‐year‐old, entire, female Boston terrier presented with chronic abdominal distention and acute anorexia. Physical examination identified a palpable abdominal mass and ascites. Results of haematological and serum biochemical investigations were within reference range.
Toshiyuki Tanaka, Mizuki Tomihari, Takashi Hasegawa   +2 more
wiley   +1 more source

Adult granulosa cell tumor associated with endometrial carcinoma: a case report

Journal of Medical Case Reports, 2011
Introduction If strict criteria for the diagnosis of carcinoma are used and all patients with granulosa cell tumors are considered, the best estimate of the incidence of associated endometrial carcinomas is under 5%.
Eke Ahizechukwu C, Eleje George U, Ikpeze Okechukwu C, Ukah Cornelius O   +3 more
doaj   +1 more source

Roles of human epididymis protein 4, carbohydrate antigen 125, inhibin B and anti-Mullerian hormone in the differential diagnosis and follow-up of ovarian granulosa cell tumors [PDF]

, 2017
Objective. Evaluation of circulating tumor markers in ovarian cancer is crucial for optimal patient care. The goal of this study was to verify the most accurate circulating tumor markers for the diagnosis and follow-up of adult-type granulosa cell tumors
Alfthan, Henrik, Farkkila, Anniina, Hallamaa, Marianne, Haltia, Ulla-Maija, Heikinheimo, Markku, Hynninen, Johanna, Kalra, Bhanu, Perheentupa, Antti, Ritvos, Olli, Tapper, Johanna, Unkila-Kallio, Leila   +10 more
core   +1 more source

Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2‐Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging

Aging Cell, Volume 25, Issue 2, February 2026.
A schematic showing decreased PTGES2 farnesylation in granulosa cells compromises PGE2‐dependent cumulus expansion and oocyte maturation during ovarian aging. In young ovaries, PTGES2 farnesylation of GCs regulates the process of cumulus expansion and oocyte maturation by facilitating PGE2 production.
Sainan Zhang, Jiahui Qi, Chuanming Liu, Huidan Zhang, Bichun Guo, Die Wu, Yicen Liu, Xin Zhen, Yang Zhang, Nannan Kang, Jidong Zhou, Guijun Yan, Chaojun Li, Lijun Ding, Haixiang Sun   +14 more
wiley   +1 more source

Delayed menopause due to granulosa cell tumor of the ovary

Journal of Mid-Life Health, 2011
A 52-year-old patient presented with complaints of menorrhagia. Endometrial biopsy revealed simple hyperplasia of the endometrium. Total abdominal hysterectomy with bilateral oophorectomy was carried out.
Bhushan Murkey, Trupti Nadkarni, Sarita Bhalerao, M J Jassawalla   +3 more
doaj   +1 more source

Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis [PDF]

, 2014
In normal ovarian function a controlled angiogenesis is essential. Several growth factors are involved in this process, such as the vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). The angiogenesis process in the normal ovary is a
Carmen Romero, Carolina Vera, Margarita Vega, Verónica Tapia   +3 more
core   +1 more source

Mechanopharmacology of cellular microenvironment stiffness: Therapeutic strategies for age‐related diseases

British Journal of Pharmacology, Volume 183, Issue 4, Page 945-956, February 2026.
Ageing brings about various biochemical, structural and mechanical alterations within tissues, profoundly impacting cellular behaviour and function. One of the hallmark changes observed with ageing is an increase in cellular microenvironment stiffness, a biomechanical property influenced by intrinsic factors within the cell and extrinsic factors from ...
Wang HaiYang, Cheong Dorothy Hui Juan, Lee Zhao‐Yong, Tran Thai   +3 more
wiley   +1 more source

The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease)

Taiwanese Journal of Obstetrics & Gynecology, 2017
Objective: Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these ...
Andrea Burgetova, Zdenek Matejovsky, Michal Zikan, Jiri Slama, Pavel Dundr, Petr Skapa, Kamila Benkova, David Cibula, Daniela Fischerova   +8 more
doaj   +1 more source

hnRNPU Safeguards Oocyte Development and Female Fertility via Regulation of Alternative Splicing

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Heterogeneous nuclear ribonucleoprotein U (hnRNPU) is essential for oocyte development and female fertility. Oocyte‐specific deletion of Hnrnpu leads to follicular arrest, impaired meiotic maturation, mitochondrial dysfunction, and infertility.
Jinmei Li, Bei Chen, Yujiao Wen, Yanqing Wu, Kuan Liu, Jingshou Chen, Shuangqi Wang, Shenglei Feng, Juan Dong   +8 more
wiley   +1 more source