Results 251 to 260 of about 78,948 (301)

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia   +11 more
wiley   +1 more source

Immunological aspects of halo nevus (Sutton's Nevus). [PDF]

open access: yesFront Immunol
Hlača N, Vičić M, Prpić-Massari L.
europepmc   +1 more source

Gut microbial metabolite butyrate boosts p53-expressing telomerase-specific oncolytic adenovirus efficacy by enhancing infectivity and activating MHC-I/cGAS-STING. [PDF]

open access: yesCancer Immunol Immunother
Sakamoto M   +18 more
europepmc   +1 more source

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus. [PDF]

open access: yesAndrology
Flammang V   +10 more
europepmc   +1 more source

TGF-β-driven NK Cells plasticity in hepatocellular carcinoma. [PDF]

open access: yesFront Immunol
Reverberi V   +15 more
europepmc   +1 more source

Granzyme A activates another way to die [PDF]

open access: yesImmunological Reviews, 2010
Summary:  Granzyme A (GzmA) is the most abundant serine protease in killer cell cytotoxic granules. GzmA activates a novel programed cell death pathway that begins in the mitochondrion, where cleavage of NDUFS3 in electron transport complex I disrupts mitochondrial metabolism and generates reactive oxygen species (ROS).
Judy Lieberman
exaly   +3 more sources

Home - About - Disclaimer - Privacy