Citrus family especially Grapefruit, has attained considerable attention due to the presence of a number of essential components that have cardiovascular and anti-hypertensive properties. The juice and essential oil extracted from eight recently released
Shahnawaz Ahmed +4 more
doaj +2 more sources
The Effect of Grapefruit Juice on the Pharmacokinetics of Tadalafil in Rats. [PDF]
We developed and validated a novel, sensitive, selective, and inexpensive high-performance liquid chromatography (HPLC) method for the determination of tadalafil in rats plasma and to investigate the effect of grapefruit juice on the pharmacokinetics of ...
Shen X, Chen F, Wang F, Huang P, Luo W.
europepmc +2 more sources
Ciprofloxacin-induced Stevens-Johnson Syndrome with Grapefruit Juice Consumption: A Case Report. [PDF]
We describe the case of a 49-year-old, otherwise healthy, Hispanic male who underwent an uncomplicated vasectomy and was treated prophylactically with a one-week course of ciprofloxacin.
Cravens MG, Sherman N, Sawaya J.
europepmc +2 more sources
Quality changes in high hydrostatic pressure and thermal pasteurized grapefruit juice during cold storage. [PDF]
Wang CY, Wang YT, Wu SJ, Shyu YT.
europepmc +2 more sources
Detecting food adulteration has always been an important task for food safety, especially when grapefruit is the adulterant as components in the juice have undesired interactions with many medicines.
Mehrvash Varnasseri, Yun Xu, R. Goodacre
semanticscholar +1 more source
Food-drug interactions precipitated by fruit juices other than grapefruit juice: An update review. [PDF]
Chen M +4 more
europepmc +2 more sources
Drug–Grapefruit Juice Interactions [PDF]
Grapefruit juice, a beverage consumed in large quantities by the general population, is an inhibitor of the intestinal cytochrome P-450 3A4 system, which is responsible for the first-pass metabolism of many medications. Through the inhibition of this enzyme system, grapefruit juice interacts with a variety of medications, leading to elevation of their ...
G C, Kane, J J, Lipsky
openaire +2 more sources
Pomelo juice–Drug interactions: A word of caution
The main of this article is to study the interactions of certain commonly used drugs with pomelo juice which is commonly consumed as easily available fruit or fruit juice in certain parts of India.
Greeshma V Shetty +3 more
doaj +1 more source
Effect of Low-Furanocoumarin Hybrid Grapefruit Juice Consumption on Midazolam Pharmacokinetics. [PDF]
Kawaguchi-Suzuki M +10 more
europepmc +2 more sources
Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat. [PDF]
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
van Ton AMP +4 more
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