Results 41 to 50 of about 65,946 (243)
BackgroundTraditional wine growing regions are increasingly endangered by climatic alterations. One promising approach to mitigate advancing climate change could be an increase of soil organic matter.
Nele Schneider +6 more
doaj +1 more source
Low-pass nanopore sequencing for measurement of global methylation levels in plants
Nanopore sequencing enables detection of DNA methylation at the same time as identification of canonical sequence. A recent study validated low-pass nanopore sequencing to accurately estimate global methylation levels in vertebrates with sequencing ...
Yusmiati Liau +8 more
doaj +1 more source
Genetic identification and characterization of Armenian grapevine cultivars
Armenia is an important area of crop origins including grapes. The objectives of this study were the molecular characterization of 38 Armenian grape genotypes and the detection of the genetic relationships between the accessions.
Nebish Anna +8 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Grapevine leafroll disease (GLD) is considered one of the most widespread grapevine virus diseases, causing severe economic losses worldwide. To date, six grapevine leafroll-associated viruses (GLRaVs) are known as causal agents of the disease, of which ...
Nele Bendel +9 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Viticulture is facing challenges, like the impact of climate change and various pests and pathogens. Alongside powdery and downy mildew, black rot is one of the most prevalent fungal diseases in European wine-growing regions.
Patricia Weber +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Grapevine leafroll-associated virus 2 and grapevine \u27Pinot gris\u27 virus are present in seedlings developed from seeds of infected grapevine plants [PDF]
Nearly 80 different viruses belonging to different genera and families have been identified in grapevines, but their seed transmissibility remains largely unclear.
Cheng, Y. Q. +6 more
core +1 more source

