Results 211 to 220 of about 5,905 (271)

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

open access: yesInterdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang   +7 more
wiley   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

open access: yesInterdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li   +15 more
wiley   +1 more source

Silica nanoparticles enhance resistance of Vitis vinifera to downy mildew. [PDF]

open access: yesBMC Plant Biol
Alfonso E   +10 more
europepmc   +1 more source

A parametric electrophysiological–transcriptomic map of MscL‐G22S sonogenetic neuromodulation in the rat hippocampus: Toward precision ultrasound neuromodulation

open access: yesJournal of Intelligent Medicine, EarlyView.
Using a factorial sweep of ultrasound fundamental and pulse repetition frequencies, we built a parametric electrophysiological–transcriptomic map of MscL‐G22S‐mediated hippocampal neuromodulation, providing reference data for precision, parameter‐aware ultrasound neuromodulation.
Xin Li   +3 more
wiley   +1 more source

First detection and tracing of grapevine red blotch virus (GRBV) in Australia using tiled amplicon sequencing. [PDF]

open access: yesArch Virol
Kinene T   +10 more
europepmc   +1 more source

Transforming Musculoskeletal Disorder Management With Multimodal AI Platform for Early Diagnosis, Self‐Screening, and Personalized Care

open access: yesMed Research, EarlyView.
We developed a multimodal large language model‐enabled framework for the early detection, self‐screening, and personalized management of major musculoskeletal disorders, including osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP).
Pengyuan Xu   +32 more
wiley   +1 more source

Evaluation of Fungal Sensitivity to Biosynthesized Copper-Oxide Nanoparticles (CuONPs) in Grapevine Tissues and Fruits. [PDF]

open access: yesJ Fungi (Basel)
Martínez-Soto D   +5 more
europepmc   +1 more source

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