Results 1 to 10 of about 902,297 (302)
High‐throughput sequencing for biology and medicine
Molecular Systems Biology, 2013 Advances in genome sequencing have progressed at a rapid pace, with increased throughput accompanied by plunging costs. But these advances go far beyond faster and cheaper. High‐throughput sequencing technologies are now routinely being applied to a wide
Wendy Weijia Soon +2 more
doaj +4 more sources
High-throughput sequencing in vaccine research [PDF]
Journal of Veterinary Research, 2021 The world of vaccines has changed tremendously since the time of Louis Pasteur. In the present day, it is regarded as vaccinology, a discipline which includes not only the knowledge of vaccine production, strategies for its delivery and influence on the ...
Pasik Katarzyna +1 more
doaj +3 more sources
High-Throughput Sequencing Technologies [PDF]
Molecular Cell, 2015 The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years.
Reuter, Jason A. +2 more
openaire +3 more sources
The Principles and Applications of High-Throughput Sequencing Technologies
Development & Reproduction, 2023 The advancement in high-throughput sequencing (HTS) technology has revolutionized the field of biology, including genomics, epigenomics, transcriptomics, and metagenomics. This technology has become a crucial tool in many areas of research, allowing scientists to generate vast amounts of genetic data at a much faster pace than traditional methods. With
Jun-Yeong Lee
openaire +3 more sources
High Throughput Sequencing for Clinical Tuberculosis: An Overview
Pathogens, 2022 High throughput sequencing (HTS) can identify the presence of Mycobacterium tuberculosis DNA in a clinical sample while also providing information on drug susceptibility.
Tara E. Ness +2 more
doaj +3 more sources
QIIME allows analysis of high-throughput community sequencing data
Nature Methods, 2010 Supplementary Figure 1 Overview of the analysis pipeline. Supplementary Table 1 Details of conventionally raised and conventionalized mouse samples. Supplementary Discussion Expanded discussion of QIIME analyses presented in the main text; Sequencing of ...
J Gregory Caporaso +2 more
exaly +2 more sources
High-throughput single-сell sequencing in cancer research
Signal Transduction and Targeted Therapy, 2022 With advances in sequencing and instrument technology, bioinformatics analysis is being applied to batches of massive cells at single-cell resolution. High-throughput single-cell sequencing can be utilized for multi-omics characterization of tumor cells,
Qingzhu Jia +4 more
doaj +2 more sources
Nature Communications, 2023 Long-read single-cell RNA isoform sequencing can elucidate the intricate landscape of alternative RNA splicing in individual cells, but it suffers from a low read throughput.
Shang-Qian Xie, Xiaochen Bo, Feng Luo
exaly +2 more sources
Compression of structured high-throughput sequencing data. [PDF]
PLoS ONE, 2013 Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to quickly adapt to
Fabien Campagne +4 more
doaj +7 more sources
Universal count correction for high-throughput sequencing.
PLoS Computational Biology, 2014 We show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions.
Tatsunori B Hashimoto +2 more
doaj +6 more sources