Results 31 to 40 of about 571,192 (299)

Reliable and accurate diagnostics from highly multiplexed sequencing assays [PDF]

, 2020
Scalable, inexpensive, and secure testing for SARS-CoV-2 infection is crucial for control of the novel coronavirus pandemic. Recently developed highly multiplexed sequencing assays (HMSAs) that rely on high-throughput sequencing can, in principle, meet ...
Bloom, Joshua S., Booeshaghi, A. Sina, Cooper, Aaron R., Gehring, Jase, Kosuri, Sriram, Lubock, Nathan B., Luebbert, Laura, Pachter, Lior, Simpkins, Scott W.   +8 more
core  

Diagnostic applications of next generation sequencing: working towards quality standards [PDF]

, 2012
Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Adey, Andrea Gehring, Anna Benet-Pagès, Bainbridge, Bentley, Carsten Bergmann, Clark, Clement, Ding, Dohm, Gerlinger, Gregory, Greif, Greif, Hanno Jörn Bolz, Hanns-Georg Klein, Harismendy, Ina Vogl, Jiang, Johansson, Kaimo Hirv, Kalari, Klaus H. Metzeler, Koboldt, Li, Lister, Loman, Mamanova, Manfred Stuhrmann, Mardis, Marius Kuhn, Mertes, Meyerson, Minoche, Nakamura, Philipp A. Greif, Robinson, Rothberg, Saskia Biskup, Sebastian H. Eck, Shendure, Stefan Kotschote, Stratton   +42 more
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From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]

, 2011
Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Adab, P., Blissett, J., Frew, E., Gill, Paramjit, Griffin, T. L., Griffith, L., Hurley, K. L., Jolly, K., Lancashire, E. R., McGee, E., Pallan, M. J., Parry, J. M., Thompson, J. L.   +12 more
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A High-Throughput Method for Illumina RNA-Seq Library Preparation. [PDF]

, 2012
With the introduction of cost effective, rapid, and superior quality next generation sequencing techniques, gene expression analysis has become viable for labs conducting small projects as well as large-scale gene expression analysis experiments. However,
Daniel H Chitwood, Jie ePeng, Julin N Maloof, Lauren R Headland, Neelima R Sinha, Ravi eKumar, Seisuke eKimura, Seisuke eKimura, Yasunori eIchihashi   +8 more
core   +2 more sources

Small molecule regulators of microRNAs identified by high-throughput screen coupled with high-throughput sequencing

Nature Communications, 2023
MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics.
Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Jiarui Zhang, Rosalia Rabinovsky, Christina R. Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young-Pearse, Stephen J. Haggarty, Anna M. Krichevsky   +11 more
doaj   +1 more source

High-throughput single-сell sequencing in cancer research

Signal Transduction and Targeted Therapy, 2022
With advances in sequencing and instrument technology, bioinformatics analysis is being applied to batches of massive cells at single-cell resolution. High-throughput single-cell sequencing can be utilized for multi-omics characterization of tumor cells,
Qingzhu Jia, Han Chu, Zheng Jin, Haixia Long, Bo Zhu   +4 more
doaj   +1 more source

Deep Sequencing Analysis of RNAs from Citrus Plants Grown in a Citrus Sudden Death-Affected Area Reveals Diverse Known and Putative Novel Viruses. [PDF]

, 2017
Citrus sudden death (CSD) has caused the death of approximately four million orange trees in a very important citrus region in Brazil. Although its etiology is still not completely clear, symptoms and distribution of affected plants indicate a viral ...
Coletta-Filho, Helvecio D, Dorta, Silvia O, Falk, Bryce W, Machado, Marcos A, Matsumura, Emilyn E, Nerva, Luca, Nouri, Shahideh, Oliveira, Tiago S   +7 more
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High Throughput Sequencing: An Overview of Sequencing Chemistry [PDF]

Indian Journal of Microbiology, 2016
In the present century sequencing is to the DNA science, what gel electrophoresis was to it in the last century. From 1977 to 2016 three generation of the sequencing technologies of various types have been developed. Second and third generation sequencing technologies referred commonly to as next generation sequencing technology, has evolved ...
Sheetal, Ambardar, Rikita, Gupta, Deepika, Trakroo, Rup, Lal, Jyoti, Vakhlu   +4 more
openaire   +2 more sources

High-throughput sequencing of a South American Amerindian. [PDF]

PLoS ONE, 2013
The emergence of next-generation sequencing technologies allowed access to the vast amounts of information that are contained in the human genome. This information has contributed to the understanding of individual and population-based variability and ...
André M Ribeiro-dos-Santos, Jorge Estefano Santana de Souza, Renan Almeida, Dayse O Alencar, Maria Silvanira Barbosa, Leonor Gusmão, Wilson A Silva, Sandro J de Souza, Artur Silva, Ândrea Ribeiro-dos-Santos, Sylvain Darnet, Sidney Santos   +11 more
doaj   +1 more source

High-Throughput Sequencing and Rare Genetic Diseases [PDF]

Molecular Syndromology, 2012
High-throughput sequencing has drastically changed the research of genes responsible for genetic disorders and is now gradually introduced as an additional genetic diagnostic testing in clinical practice. The current debates on the emerging technical, medical and ethical issues as well as the potential optimum use of the available technology are ...
Makrythanasis P, Antonarakis SE.
openaire   +3 more sources