Results 31 to 40 of about 15,584,188 (261)
Special features of RAD Sequencing data:implications for genotyping [PDF]
, 2012 Restriction site-associated DNA Sequencing (RAD-Seq) is an economical and efficient method for SNP discovery and genotyping. As with other sequencing-by-synthesis methods, RAD-Seq produces stochastic count data and requires sensitive analysis to develop ...
Fuentes-Utrilla, Pablo +12 more
core +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundBacterial vaginosis (BV) is characterized by reduced Lactobacillus dominance and enrichment of anaerobic bacteria. Although BV has been associated with human papillomavirus (HPV) infection, its relationship with cytologic abnormalities and ...
Zhen Li +12 more
doaj +1 more source
High-throughput single-сell sequencing in cancer research
Signal Transduction and Targeted Therapy, 2022 With advances in sequencing and instrument technology, bioinformatics analysis is being applied to batches of massive cells at single-cell resolution. High-throughput single-cell sequencing can be utilized for multi-omics characterization of tumor cells,
Qingzhu Jia +4 more
doaj +1 more source
Scrutinizing virus genome termini by high-throughput sequencing. [PDF]
PLoS ONE, 2014 Analysis of genomic terminal sequences has been a major step in studies on viral DNA replication and packaging mechanisms. However, traditional methods to study genome termini are challenging due to the time-consuming protocols and their inefficiency ...
Shasha Li +6 more
doaj +1 more source
estMOI: estimating multiplicity of infection using parasite deep sequencing data. [PDF]
, 2014 Individuals living in endemic areas generally harbour multiple parasite strains. Multiplicity of infection (MOI) can be an indicator of immune status and transmission intensity.
Sutherland, Colin J +5 more
core +1 more source
High-throughput sequencing of intrahepatic RNA from HAV-infected mice.
, 2021 High-throughput sequencing of intrahepatic RNA from HAV-infected mice.
Ganes C. Sen (9708002) +12 more
core +1 more source
Compression of structured high-throughput sequencing data.
PLoS ONE, 2013 Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to quickly adapt to
Fabien Campagne +4 more
doaj +1 more source
High-throughput sequencing of a South American Amerindian. [PDF]
PLoS ONE, 2013 The emergence of next-generation sequencing technologies allowed access to the vast amounts of information that are contained in the human genome. This information has contributed to the understanding of individual and population-based variability and ...
André M Ribeiro-dos-Santos +11 more
doaj +1 more source
Microfluidic Technologies for High-Throughput Screening Applications [PDF]
, 2003 In this thesis, I present a strategy for the design and development of microfluidic devices for high-throughput screening applications, such as mutant enzyme libraries expressed in prokaryotic hosts, where a few point mutations at the DNA level ...
Thorsen, Todd Addison
core +1 more source
High-throughput sequencing: a failure mode analysis
BMC Genomics, 2005 Background Basic manufacturing principles are becoming increasingly important in high-throughput sequencing facilities where there is a constant drive to increase quality, increase efficiency, and decrease operating costs.
Marra Marco A +6 more
doaj +1 more source