Results 41 to 50 of about 571,192 (299)

Probing the connectivity of neural circuits at single-neuron resolution using high-throughput DNA sequencing [PDF]

, 2011
There is growing excitement in determining the complete connectivity diagram of the brain—the "connectome". So far, the complete connectome has been established for only one organism, C.
Alex Koulakov, Anthony Zador, Gang Cao, Hassana Oyibo, Huiqing Zhan, Joshua Dubnau, Lynn Enquist   +6 more
core   +2 more sources

Universal count correction for high-throughput sequencing.

PLoS Computational Biology, 2014
We show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions.
Tatsunori B Hashimoto, Matthew D Edwards, David K Gifford   +2 more
doaj   +1 more source

ReSeq simulates realistic Illumina high-throughput sequencing data

Genome Biology, 2021
In high-throughput sequencing data, performance comparisons between computational tools are essential for making informed decisions at each step of a project.
Stephan Schmeing, Mark D. Robinson
doaj   +1 more source

High-throughput DNA sequencing to survey bacterial histidine and tyrosine decarboxylases in raw milk cheeses [PDF]

, 2015
peer-reviewedBackground The aim of this study was to employ high-throughput DNA sequencing to assess the incidence of bacteria with biogenic amine (BA; histamine and tyramine) producing potential from among 10 different cheeses varieties.
Cotter, Paul D., Fallico, Vincenzo, Giblin, Linda, McSweeney, Paul L. H., O'Sullivan, Daniel, O'Sullivan, Orla, Sheehan, Diarmuid (JJ)   +6 more
core   +1 more source

Transcriptome-Wide High-Throughput m6A Sequencing of Differential m6A Methylation Patterns in the Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes Cell Line MH7A

Journal of Inflammation Research, 2021
Hui Jiang1,2 *,* Kefeng Cao3 *,* Chang Fan,1,2 Xiaoya Cui,1,2 Yanzhen Ma,1,2 Jian Liu1 1Experimental Center of Clinical Research, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2School ...
Jiang H, Cao K, Fan C, Cui X, Ma Y, Liu J   +5 more
doaj  

Efficient COI barcoding using high throughput single-end 400 bp sequencing

BMC Genomics, 2020
Background Over the last decade, the rapid development of high-throughput sequencing platforms has accelerated species description and assisted morphological classification through DNA barcoding. However, the current high-throughput DNA barcoding methods
Chentao Yang, Yuxuan Zheng, Shangjin Tan, Guanliang Meng, Wei Rao, Caiqing Yang, David G. Bourne, Paul A. O’Brien, Junqiang Xu, Sha Liao, Ao Chen, Xiaowei Chen, Xinrui Jia, Ai-bing Zhang, Shanlin Liu   +14 more
doaj   +1 more source

Scrutinizing virus genome termini by high-throughput sequencing. [PDF]

PLoS ONE, 2014
Analysis of genomic terminal sequences has been a major step in studies on viral DNA replication and packaging mechanisms. However, traditional methods to study genome termini are challenging due to the time-consuming protocols and their inefficiency ...
Shasha Li, Hang Fan, Xiaoping An, Huahao Fan, Huanhuan Jiang, Yubao Chen, Yigang Tong   +6 more
doaj   +1 more source

Methods to study splicing from high-throughput RNA Sequencing data

, 2015
The development of novel high-throughput sequencing (HTS) methods for RNA (RNA-Seq) has provided a very powerful mean to study splicing under multiple conditions at unprecedented depth. However, the complexity of the information to be analyzed has turned
A Ameur, A Bhasi, A Dobin, A Mortazavi, A Oshlack, A Roberts, A Roberts, AM Mezlini, AN Brooks, B Jackson, B Kakaradov, B Langmead, B Li, B Li, BJ Haas, BJ Haas, C Trapnell, C Trapnell, C Trapnell, D Hiller, D Singh, DL Wood, DW Bryant, E Eyras, E Lee, E Turro, ET Wang, F Birzele, F Bona De, F Denoeud, F Tang, G Robertson, G Xu, GA Sacomoto, GR Grant, GS Slater, H Bao, H Jiang, H Jiang, H Kim, H Richard, J Behr, J Du, J Feng, J Hu, J Lovén, J Martin, J Salzman, J Seok, J Seok, J Wu, J Wu, JE Allen, JJ Li, JP Venables, K Schneeberger, K Wang, KD Hansen, KF Au, KL Howe, KM Borgwardt, L Chen, L Chen, L Wang, L Wang, LY Chen, M Aschoff, M Fiume, M Garber, M Griffith, M Guttman, M Stanke, M Stanke, M Sultan, MC Ryan, MF Rogers, MG Grabherr, MH Schulz, MT Dimon, N Cloonan, N Cloonan, N Deng, N Leng, N Nicolae, N Philippe, N Vijay, NA Fonseca, O Stegle, P Drewe, P Glaus, PL Martelli, PP Labaj, Q Liu, Q Liu, Q Pan, QY Zhao, R Bohnert, R Guigó, R Li, S Anders, S Djebali, S Filichkin, S Heber, S Huang, S Lee, S Mangul, S Marco-Sola, S Shen, S Sonnenburg, S Srivastava, S Tang, S Zheng, SB Montgomery, SH Nagaraj, SK Lou, T Bonfert, TA Clark, TD Wu, TD Wu, W Li, W Li, W Wang, WJ Kent, Y Hu, Y Katz, Y Li, Y Liao, Y Surget-Groba, Y Xing, Y Xing, Y Zhang, Z Xia   +131 more
core   +1 more source

YAMAT-seq: an efficient method for high-throughput sequencing of mature transfer RNAs. [PDF]

, 2017
Besides translation, transfer RNAs (tRNAs) play many non-canonical roles in various biological pathways and exhibit highly variable expression profiles.
Honda, Shozo, Kirino, Yohei, Loher, Phillipe, Rigoutsos, Isidore, Shigematsu, Megumi, Telonis, Aristeidis G.   +5 more
core   +2 more sources

Diverse and widespread contamination evident in the unmapped depths of high throughput sequencing data [PDF]

, 2014
Background: Trace quantities of contaminating DNA are widespread in the laboratory environment, but their presence has received little attention in the context of high throughput sequencing.
Lusk, Richard W
core   +6 more sources