Results 41 to 50 of about 16,449,464 (307)

Spatiotemporal characteristics of environmental microbial communities and resistomes in intensive care units of a tertiary hospital in northwest China

Frontiers in Microbiology
BackgroundIntensive care units (ICUs) are high-risk settings for healthcare-acquired infections (HAIs). It is essential to characterize the microorganisms and antimicrobial resistance genes (ARGs) in ICU environments for prevention and control of HAIs ...
Jiexi Yan, Jiexi Yan, Qingmiao Ren, Qingmiao Ren, Xiaomin He, Haiyun Du, Haiyun Du, Lijuan He, Zhaoyu Zheng, Zhaoyu Zheng, Yaya Qi, Yaya Qi, Xiaohong Xian, Xiaohong Xian   +13 more
doaj   +1 more source

Optimal assembly for high throughput shotgun sequencing [PDF]

BMC Bioinformatics, 2013
We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in terms of the repeat statistics of the genome.
Bresler, Guy, Bresler, Ma'ayan, Tse, David   +2 more
openaire   +5 more sources

Morphology-defined bacterial vaginosis and HPV-related cervical screening abnormalities: a two-year real-world study with histopathologic correlation

Frontiers in Cellular and Infection Microbiology
BackgroundBacterial vaginosis (BV) is characterized by reduced Lactobacillus dominance and enrichment of anaerobic bacteria. Although BV has been associated with human papillomavirus (HPV) infection, its relationship with cytologic abnormalities and ...
Zhen Li, Zhen Li, Zhi Duan, Zhi Duan, Ran Liu, Ran Liu, Siwei Yu, Siwei Yu, Ning Wang, Hui Chen, Hui Chen, Qimei Xu, Qimei Xu   +12 more
doaj   +1 more source

Small molecule regulators of microRNAs identified by high-throughput screen coupled with high-throughput sequencing

Nature Communications, 2023
MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics.
Lien D. Nguyen, Zhiyun Wei, M. Catarina Silva, Sergio Barberán-Soler, Jiarui Zhang, Rosalia Rabinovsky, Christina R. Muratore, Jonathan M. S. Stricker, Colin Hortman, Tracy L. Young-Pearse, Stephen J. Haggarty, Anna M. Krichevsky   +11 more
doaj   +1 more source

Lower peripheral T- and NK-cell counts are associated with systemic inflammation and nutritional status in hospitalized gastrointestinal surgery patients

Frontiers in Medicine
BackgroundSystemic inflammation and impaired nutritional status may be associated with altered cellular immune profiles in surgical inpatients. However, peripheral T- and NK-cell profiles and their clinical correlates remain insufficiently characterized ...
Zhi Duan, Zhi Duan, Xiangjuan Jiao, Xiangjuan Jiao, Ning Wang, Wubin Zhou, Jiao He, Jiao He, Lingyong Liu, Lingyong Liu, Qi Zuo, Zhen Li, Zhen Li   +12 more
doaj   +1 more source

High-throughput single-сell sequencing in cancer research

Signal Transduction and Targeted Therapy, 2022
With advances in sequencing and instrument technology, bioinformatics analysis is being applied to batches of massive cells at single-cell resolution. High-throughput single-cell sequencing can be utilized for multi-omics characterization of tumor cells,
Qingzhu Jia, Han Chu, Zheng Jin, Haixia Long, Bo Zhu   +4 more
doaj   +1 more source

High-throughput sequencing raw data

, 2018
High-throughput sequencing raw data for 3 samples（Read1）, A1;A2;A3 are three samples from control ...
Manxin Fang (5768321)
core   +1 more source

Scrutinizing virus genome termini by high-throughput sequencing. [PDF]

PLoS ONE, 2014
Analysis of genomic terminal sequences has been a major step in studies on viral DNA replication and packaging mechanisms. However, traditional methods to study genome termini are challenging due to the time-consuming protocols and their inefficiency ...
Shasha Li, Hang Fan, Xiaoping An, Huahao Fan, Huanhuan Jiang, Yubao Chen, Yigang Tong   +6 more
doaj   +1 more source

High-throughput sequencing of a South American Amerindian. [PDF]

PLoS ONE, 2013
The emergence of next-generation sequencing technologies allowed access to the vast amounts of information that are contained in the human genome. This information has contributed to the understanding of individual and population-based variability and ...
André M Ribeiro-dos-Santos, Jorge Estefano Santana de Souza, Renan Almeida, Dayse O Alencar, Maria Silvanira Barbosa, Leonor Gusmão, Wilson A Silva, Sandro J de Souza, Artur Silva, Ândrea Ribeiro-dos-Santos, Sylvain Darnet, Sidney Santos   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source