Results 21 to 30 of about 322,188 (262)
High-Throughput Microdissection for Next-Generation Sequencing. [PDF]
PLoS ONE, 2016 Precision medicine promises to enhance patient treatment through the use of emerging molecular technologies, including genomics, transcriptomics, and proteomics.
Avi Z Rosenberg +17 more
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High Throughput Sequencing for Detection of Foodborne Pathogens
Frontiers in Microbiology, 2017 High-throughput sequencing (HTS) is becoming the state-of-the-art technology for typing of microbial isolates, especially in clinical samples. Yet, its application is still in its infancy for monitoring and outbreak investigations of foods.
Camilla Sekse +6 more
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Frontiers in Microbiology, 2021 Mucoromycotina are often considered mainly in pathogenic context but their biology remains understudied. We describe the genomes of six Mucoromycotina fungi representing distant saprotrophic lineages within the subphylum (i.e., Umbelopsidales and ...
Anna Muszewska +14 more
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Ion torrent high throughput mitochondrial genome sequencing (HTMGS).
PLoS ONE, 2019 The implementation and popularity of next generation sequencing (NGS) has led to the development of various rapid whole mitochondrial genome sequencing techniques. We summarise an efficient and cost-effective NGS approach for mitochondrial genomic DNA in
N R Harvey +10 more
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First occurrence of bidens mottle virus in Brazil: biological and molecular characterization of isolates infecting Zinnia sp. and Bidens pilosa [PDF]
Scientia Agricola, 2023 Zinnia sp. and hairy beggartick (Bidens pilosa) plants exhibiting symptoms of possible virus infection were found in the municipality of Santa Bárbara d’Oeste, São Paulo State, Brazil.
Gabriel Madoglio Favara +8 more
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Targeted high throughput sequencing in hereditary ataxia and spastic paraplegia. [PDF]
PLoS ONE, 2017 Hereditary ataxia and spastic paraplegia are heterogeneous monogenic neurodegenerative disorders. To date, a large number of individuals with such disorders remain undiagnosed.
Zafar Iqbal +8 more
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Optimal assembly for high throughput shotgun sequencing [PDF]
BMC Bioinformatics, 2013 We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in terms of the repeat statistics of the genome.
Bresler, Guy +2 more
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High-Throughput Sequencing and Rare Genetic Diseases [PDF]
Molecular Syndromology, 2012 High-throughput sequencing has drastically changed the research of genes responsible for genetic disorders and is now gradually introduced as an additional genetic diagnostic testing in clinical practice. The current debates on the emerging technical, medical and ethical issues as well as the potential optimum use of the available technology are ...
Makrythanasis P, Antonarakis SE.
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Nature Communications, 2023 MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics.
Lien D. Nguyen +11 more
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Frontiers in Cellular and Infection MicrobiologyBackgroundBacterial vaginosis (BV) is characterized by reduced Lactobacillus dominance and enrichment of anaerobic bacteria. Although BV has been associated with human papillomavirus (HPV) infection, its relationship with cytologic abnormalities and ...
Zhen Li +12 more
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