Results 11 to 20 of about 16,449,464 (307)
Universal count correction for high-throughput sequencing.
PLoS Computational Biology, 2014 We show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions.
Tatsunori B Hashimoto +2 more
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Compression of structured high-throughput sequencing data. [PDF]
PLoS ONE, 2013 Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to quickly adapt to
Fabien Campagne +4 more
doaj +7 more sources
Drug Design, Development and Therapy, 2015 Aicui Liu,1,2,* Chao Wang,1,2,* Zhijuan Liang,3 Zhi-Wei Zhou,4 Lin Wang,1,2 Qiaoli Ma,1,2 Guowei Wang,1,2 Shu-Feng Zhou,4 Zhenhai Wang1,2 1Neurology Center, General Hospital of Ningxia Medical University, Yinchuan, Ningxia; 2Key Laboratory of Brain ...
Liu A +8 more
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High-Throughput Sequencing Technologies [PDF]
Molecular Cell, 2015 The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years.
Reuter, Jason A. +2 more
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High‐throughput sequencing of the melanoma genome [PDF]
Experimental Dermatology, 2012 AbstractNext‐generation sequencing technologies are now common for whole‐genome, whole‐exome and whole‐transcriptome sequencing (RNA‐seq) of tumors to identify point mutations, structural or copy number alterations and changes in gene expression. A substantial number of studies have already been performed for melanoma. One study analysed eight melanoma
Kunz, M. +2 more
openaire +3 more sources
High-throughput Phenotyping with Temporal Sequences [PDF]
Journal of the American Medical Informatics Association, 2019 ABSTRACT Objective High-throughput electronic phenotyping algorithms can accelerate translational research using data from electronic health record (EHR) systems. The temporal information buried in EHRs are often underutilized in developing computational phenotypic definitions.
Estiri, Hossein +5 more
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High Throughput Sequencing: An Overview of Sequencing Chemistry [PDF]
Indian Journal of Microbiology, 2016 In the present century sequencing is to the DNA science, what gel electrophoresis was to it in the last century. From 1977 to 2016 three generation of the sequencing technologies of various types have been developed. Second and third generation sequencing technologies referred commonly to as next generation sequencing technology, has evolved ...
Sheetal, Ambardar +4 more
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Diagnostic applications of next generation sequencing: working towards quality standards [PDF]
, 2012 Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Klein, Hanns-Georg +27 more
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High‐Throughput Multiplex Sequencing of miRNA [PDF]
Current Protocols in Human Genetics, 2012 AbstractNext‐generation sequencing offers many advantages over other methods of microRNA (miRNA) expression profiling, such as sample throughput and the capability to discover novel miRNAs. As the sequencing depth of current sequencing platforms exceeds what is necessary to quantify miRNAs, multiplexing several samples in one sequencing run offers a ...
Francois, Vigneault +7 more
openaire +2 more sources
High-throughput sequencing of intrahepatic RNA from HAV-infected mice.
, 2021 High-throughput sequencing of intrahepatic RNA from HAV-infected mice.
Ganes C. Sen (9708002) +12 more
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