Results 221 to 230 of about 12,232 (300)

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Virome analysis of mango reveals mangifera indica latent virus, a benyvirus and a novel olivavirus. [PDF]

Virol J
Prajapati MR, Shimray MY, Gehlot J, Tiwari A, Singh D, Gupta N, Baranwal VK, Sharma SK.   +7 more
europepmc   +1 more source

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

Exploration, EarlyView.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu, Xue Xia, Yingfang Chen, Haoying Yang, Xiaochen Chen, Lei Cai, Bingyang Shi   +6 more
wiley   +1 more source

Genome characterization of prunus maculavirus 1 (PrMcV-1), a novel member of the genus maculavirus identified in prunus spp. [PDF]

Arch Virol
Abou Kubaa R, Ouro-Djobo A, Stevens KA, Alabi OJ, Al Rwahnih M.   +4 more
europepmc   +1 more source

Rumen Mycobiome Thiamine Metabolism Contributes to Subacute Rumen Acidosis Tolerance in Goats Through Enhancing Epithelial Cell Proliferation via IGFBP2/IGF1 Axis Activation

Exploration, EarlyView.
Schematic illustration of the mechanism underlying the differences between SARA‐susceptible and SARA‐tolerant dairy goats fed a high‐concentrate diet. SARA‐susceptible goats (HCS) exhibit low rumen pH and metabolic decline, characterized by epithelial inflammation.
Jingyi Xu, Xiaodong Chen, Yi Ma, Jianrong Ren, Guanghao Xu, Peilin Zhang, Wenhao Jia, Quanqiu Deng, Yuquan Xiao, Junhu Yao, Shengru Wu   +10 more
wiley   +1 more source

Inhibitory Effects of Garlic Extract on Hop Stunt Viroid in Micropropagated Grapevine Plantlets. [PDF]

Plant Pathol J
Kang CM, Jeong RD.
europepmc   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source

Exploring intra-varietal variation for complex traits in grapevine (Vitis vinifera L.). [PDF]

Theor Appl Genet
Robinson H, Strack T, Schmidt M, Callipo P, Nsibi M, Schmid J, Rühl E, Piepho HP, Voss-Fels KP.   +8 more
europepmc   +1 more source

Navigating the Dual Pandemics: Challenges to Faculty Diversity and Student Success

New Directions for Community Colleges, EarlyView.
Lorenzo Baber, Karla Velasco, Jeongsan Hwang, Gianina Baker   +3 more
wiley   +1 more source

Recent advances in multifunctional soft robots: A materials–structures–systems co‐design perspective for synergistic integration

FlexMat, EarlyView.
Abstract Soft robots, engineered from highly compliant materials, offer superior adaptability and safety in unstructured environments compared to their rigid counterparts. Recent advancements, fueled by bio‐inspiration and material programmability, have led to the rapid co‐evolution of their core modules: actuation, sensing, protection, energy, and ...
Qiulei Liu, Zicao Peng, Chong Sun, Haitao Yang   +3 more
wiley   +1 more source