Results 81 to 90 of about 5,905 (271)
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Development of a universal RT-PCR assay for grapevine vitiviruses.
PLoS ONE, 2020 The genus Vitivirus in the family Betaflexiviridae includes eleven viruses known to infect grapevine: grapevine vitiviruses A, B, D, E, F, G, H, I, J, L and M (GVA-GVM).
Alfredo Diaz-Lara +3 more
doaj +1 more source
Analyzes of mealybug (Pseudococcus longispinus) virome reveal grapevine viruses diversity. [PDF]
The long-tailed mealybug, Pseudococcus longispinus, is an important insect pest in grapevine growing areas in several countries, including Brazil.
GRYNBERG, P. +5 more
core +1 more source
Traditional Approaches and Emerging Biotechnologies in Grapevine Virology
, 2023 Environmental changes and global warming may promote the emergence of unknown viruses, whose spread is favored by the trade in plant products. Viruses represent a major threat to viticulture and the wine industry.
Giulia Tarquini +3 more
core +1 more source
Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis
Advanced Science, EarlyView.This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou +23 more
wiley +1 more source
Monitoring the Spread of Grapevine Viruses in Vineyards of Contrasting Agronomic Practices: A Metagenomic Investigation. [PDF]
Biology (Basel), 2023 Vu M, McFadden-Smith W, Poojari S.
europepmc +1 more source
A Diverse Virome of Leafroll-Infected Grapevine Unveiled by dsRNA Sequencing
, 2020 Quebec is the third-largest wine grape producing province in Canada, and the industry is constantly expanding. Traditionally, 90% of the grapevine cultivars grown in Quebec were winter hardy and largely dominated by interspecific hybrid Vitis sp ...
Mamadou L. Fall +5 more
core +1 more source
Advanced Science, EarlyView.The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis +32 more
wiley +1 more source
Resistance to viruses, phytoplasmas and their vectors in the grapevine in Europe: a review
, 2009 Control of grapevine virus and phytoplasma diseases is currently based on prophylactic measures and cultural practices. Certification programs aim to avoid the introduction of diseased grapevines into healthy vineyards, and cultural practices aim to reduce the populations of virus vectors to limit virus spread.
M. Laimer +6 more
openaire +4 more sources
Advanced Science, EarlyView.In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin +13 more
wiley +1 more source