Results 91 to 100 of about 5,338,929 (295)

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Graph-Based Automation of Threat Analysis and Risk Assessment for Automotive Security

open access: yesInformation
The proliferation of cyber–physical systems in modern vehicles, characterized by densely interconnected Electronic Control Units (ECUs) and heterogeneous communication networks, has significantly expanded the automotive attack surface. Traditional Threat
Mera Nizam-Edden Saulaiman   +2 more
doaj   +1 more source

Improving the Computational Performance of Ontology-Based Classification Using Graph Databases

open access: yesRemote Sensing, 2015
The increasing availability of very high-resolution remote sensing imagery (i.e., from satellites, airborne laser scanning, or aerial photography) represents both a blessing and a curse for researchers.
Thomas J. Lampoltshammer   +1 more
doaj   +1 more source

Benchmarking Database Systems for Graph Pattern Matching

open access: yes, 2014
In graph pattern matching the task is to find inside a given graph some specific smaller graph, called pattern. One way of solving this problem is to express it in the query language of a database system.
Skritek, Sebastian   +7 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Converting relational to graph databases

open access: yes, 2013
"Graph Database Management Systems provide an effective and efficient solution to data storage in current scenarios where data are more and more connected, graph models are widely used, and systems need to scale to large data sets. In this framework, the
DE VIRGILIO, ROBERTO   +5 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Research on power system carbon flow calculation based on graph database and graph computing engine

open access: yes大数据
Firstly, the basic principles of graph database and graph algorithms are introduced, including the data model of graph database, query language, and common graph algorithms.Then, the method of constructing the graph model of the power system is ...
Guangxin ZHU   +5 more
doaj  

Freight truckload marketplace: routes recommendation with a spatio-temporal graph approach

open access: yesKuwait Journal of Science
This paper presents a digital freight platform based on a spatio-temporal graph to foster collaboration between shippers and carriers. It offers a data-driven approach to address the complexities of freight transport planning by considering geographical ...
Abdelghani Saoud   +3 more
doaj   +1 more source

Usage of a graph database for the selection of sterile items in the OR. [PDF]

open access: yesInt J Comput Assist Radiol Surg, 2023
Müller C, Bernhard L, Wilhelm D.
europepmc   +1 more source

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