Results 71 to 80 of about 272,337 (306)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
The business of culture, a single subject community: lessons from The Culturist
Digital Studies, 2017 TheCulturist.ca is the result of a term long course within the Digital Humanities Minor for undergraduate students, worked on in collaboration with the CulturePlex Lab at Western University.
Antonio Jimenez-Mavillard +3 more
doaj +1 more source
House of Graphs 2.0: A database of interesting graphs and more
Discrete Applied Mathematics, 2023 In 2012 we announced the House of Graphs (https://houseofgraphs.org) [Discrete Appl. Math. 161 (2013), 311-314], which was a new database of graphs. The House of Graphs hosts complete lists of graphs of various graph classes, but its main feature is a searchable database of so called "interesting" graphs, which includes graphs that already occurred as ...
Coolsaet, Kris +2 more
openaire +4 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Temporal Graph Analysis using Gradoop [PDF]
, 2019 The temporal analysis of evolving graphs is an important requirement in many domains but hardly supported in current graph database and graph processing systems.
Thor, Andreas +2 more
core +1 more source
Towards open data blockchain analytics: a Bitcoin perspective [PDF]
Royal Society Open Science, 2018 Bitcoin is the first implementation of a technology that has become known as a ‘public permissionless’ blockchain. Such systems allow public read/write access to an append-only blockchain database without the need for any mediating central authority ...
D. McGinn, D. McIlwraith, Y. Guo
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Creating an Intelligent System for Bankruptcy Detection: Semantic data Analysis Integrating Graph Database and Financial Ontology [PDF]
, 2019 In this paper, we propose a novel intelligent methodology to construct a Bankruptcy Prediction Computation Model, which is aimed to execute a company’s financial status analysis accurately.
Yerashenia, N., Bolotov, A.
core
A GRAPH-ORIENTED OBJECT DATABASE MODEL [PDF]
, 1994 A graph-oriented object database model (GOOD) is introduced as a theoretical basis for database systems in which manipulation as well as conceptual representation of data is transparently graph-based. In the GOOD model, the scheme as well as the instance
VAN DEN BUSSCHE, +3 more
core +5 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source