Results 81 to 90 of about 3,576,657 (341)

A semantic graph database for the interoperability of 3D GIS data

open access: yesApplied Geomatics, 2020
In the last decades, the use of information management systems in the building data processing led to radical changes to the methods of data production, documentation and archiving. In particular, the possibilities, given by these information systems, to
E. Malinverni   +5 more
semanticscholar   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The business of culture, a single subject community: lessons from The Culturist

open access: yesDigital Studies, 2017
TheCulturist.ca is the result of a term long course within the Digital Humanities Minor for undergraduate students, worked on in collaboration with the CulturePlex Lab at Western University.
Antonio Jimenez-Mavillard   +3 more
doaj   +1 more source

House of Graphs 2.0: A database of interesting graphs and more

open access: yesDiscrete Applied Mathematics, 2023
In 2012 we announced the House of Graphs (https://houseofgraphs.org) [Discrete Appl. Math. 161 (2013), 311-314], which was a new database of graphs. The House of Graphs hosts complete lists of graphs of various graph classes, but its main feature is a searchable database of so called "interesting" graphs, which includes graphs that already occurred as ...
Coolsaet, Kris   +2 more
openaire   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Anatomy of a Data Science Software Toolkit That Uses Machine Learning to Aid ‘Bench-to-Bedside’ Medical Research—With Essential Concepts of Data Mining and Analysis Explained

open access: yesApplied Sciences, 2021
Data science and machine learning are buzzwords of the early 21st century. Now pervasive through human civilization, how do these concepts translate to use by researchers and clinicians in the life-science and medical field?
László Beinrohr   +5 more
doaj   +1 more source

Creating an Intelligent System for Bankruptcy Detection: Semantic data Analysis Integrating Graph Database and Financial Ontology [PDF]

open access: yes, 2019
In this paper, we propose a novel intelligent methodology to construct a Bankruptcy Prediction Computation Model, which is aimed to execute a company’s financial status analysis accurately.
Yerashenia, N., Bolotov, A.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Towards open data blockchain analytics: a Bitcoin perspective [PDF]

open access: yesRoyal Society Open Science, 2018
Bitcoin is the first implementation of a technology that has become known as a ‘public permissionless’ blockchain. Such systems allow public read/write access to an append-only blockchain database without the need for any mediating central authority ...
D. McGinn, D. McIlwraith, Y. Guo
doaj   +1 more source

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