Results 81 to 90 of about 5,338,929 (295)

Analisis Performansi Metode Graph Decomposition Index pada Graph Database [PDF]

, 2015
Kekurangan relational database yang ditemui, seperti sulitnya membuat desain relational database yang pas, kurang mampu mengakomodir data semi terstruktur, dan kurang mampunya mengakomodir data yang memiliki banyak relasi mendorong para peneliti untuk ...
ISJHAR KAUTSAR
core  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Combined graph/relational database management system for calculated chemical reaction pathway data [PDF]

, 2020
Presently, quantum chemical calculations are widely used to generate extensive data sets for machine learning applications; however, generally, these sets only include information on equilibrium structures and some close conformers.
Timur, Madzhidov, Sidorov P., Pavel, Sidorov, Timur, Gimadiev, Varnek A., Gimadiev T., Nugmanov R., Ramil, Nugmanov, Dinar, Batyrshin, Alexandre, Varnek, Maeda S., Madzhidov T., Batyrshin D., Satoshi, Maeda   +13 more
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Implementasi Prinsip MDL untuk Kompresi Graph Database Menggunakan Algoritma Greedy [PDF]

, 2015
# **ABSTRAK** # *Graph* secara konsep merupakan abstraksi yang secara fundamental telah lama dipakai, yang memungkinkan untuk memodelkan sistem dunia nyata. Begitu pula pada data, data jenis apapun dapat dimodelkan relasi antar data tersebut menggunakan *
HARRIS FEBRYANTONY Z
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Graph Harvester (Software Abstract)

We present Graph Harvester, a website for extracting graphs from illustrations in scientific papers. For every graph that has been extracted, Graph Harvester queries the graph database House of Graphs.
Hegemann, Tim, Deynet, Julius, Kempf, Sebastian, Wolff, Alexander   +3 more
core   +1 more source

G-CORE a core for future graph query languages

, 2018
We report on a community effort between industry and academia to shape the future of graph query languages. We argue that existing graph database management systems should consider supporting a query language with two key characteristics.
Gutierrez, Claudio, Plantikow, Stefan, Arenas, Marcelo, Lindaaker, Tobias, Das, Gautam, Boncz, Peter, Voigt, Hannes, Fletcher, George, Eldawy, Ahmed, van Rest, Oskar, Sequeda, Juan, Jermaine, Christopher, Angles, Renzo, Barceló, Pablo, Paradies, Marcus, Bernstein, Philip   +15 more
core   +1 more source