Results 71 to 80 of about 829,286 (307)

Spatial search by quantum walk

open access: yes, 2003
Grover's quantum search algorithm provides a way to speed up combinatorial search, but is not directly applicable to searching a physical database. Nevertheless, Aaronson and Ambainis showed that a database of N items laid out in d spatial dimensions can
A. Ambainis   +9 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Implementing Graph-based Search Engine using Sparksee Graph Database [PDF]

open access: yes, 2015
The purpose of this project is to implement basic search engine which is based on graph data by using graph database. The data used in this project comes from the Marvel Chronology Project which includes all the characteristics in Marvel Universe and ...
Zhou, Jie
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

A Graph Data Model for CityGML Utility Network ADE: A Case Study on Water Utilities

open access: yesISPRS International Journal of Geo-Information
Modelling connectivity in utility networks is essential for operational management, maintenance planning, and resilience analysis. The CityGML Utility Network Application Domain Extension (UNADE) provides a detailed conceptual framework for representing ...
Ensiyeh Javaherian Pour   +4 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Towards inheritance in graph databases

open access: yes2018 International Conference on Information Management and Processing (ICIMP), 2018
Object-oriented database management systems represent a technology in which the concepts of the object-oriented programming paradigm are implemented in databases. The impedance mismatch problem between different technologies (e.g., relational and object-oriented) has represented a challenge for developers and researchers for many years now.
Šestak, Martina, Rabuzin, Kornelije
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Knowledge and agent-based system for decentralised scheduling in manufacturing

open access: yesCogent Engineering, 2019
The aim of the research paper is to develop algorithms for manufacturers’ agents that would allow them to sequence their own operation plans and to develop a multi-agent infrastructure to allow operation pair agents to cooperatively adjust the timing of ...
Salman Saeidlou   +2 more
doaj   +1 more source

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