Results 61 to 70 of about 1,499,664 (294)

Graph databases a comparativeanalysis

open access: yes, 2023
I dagens samhälle är energieffektivisering en viktig parameter när man pratar om hållbar-het. Många fastigheter saknar tekniska lösningar för att effektivt övervaka och hantera en-ergiförbrukning. För att möta detta behov strävar företag som iquest efter
Lindström, Kasper, Lindqvist, Jonathan
core   +3 more sources

Using SPARQL to access Linked Open Data

open access: yesThe Programming Historian, 2015
This lesson explains why many cultural institutions are adopting graph databases, and how researchers can access these data though the query language called SPARQL.
Matthew Lincoln
doaj  

Analyzing The Encountered Problems and Possible Solutions of Converting Relational Databases to Graph Databases

open access: yesJournal of Advanced Research in Natural and Applied Sciences, 2022
Relational database management systems have been used for storing data for a long time.However, these systems are insufficient to analyze the large and complex structure of the data.
Ramazan Altın, A. Cumhur Kınacı
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Graph Pattern Matching: From Intractable to Polynomial Time [PDF]

open access: yes, 2010
Graph pattern matching is typically defined in terms of sub-graph isomorphism, which makes it an np-complete problem. Moreover, it requires bijective functions, which are often too restrictive to characterize patterns in emerging applications. We propose
Li, Jianzhong   +5 more
core  

Query Evaluation in Deductive Databases [PDF]

open access: yes, 1990
It is desirable to answer queries posed to deductive databases by computing fixpoints because such computations are directly amenable to set-oriented fact processing.
Bry, François
core   +1 more source

Relational database and graph database: A comparative analysis [PDF]

open access: yesJournal of Process Management. New Technologies, 2017
Since 1970, relational database models have been in use for storing, manipulating and retrieving data. The importance of relational databases is going to decrease due to the exponential growth of data as it is difficult to work with large number of joining tables.
Surajit Medhi, Hemanta K. Baruah
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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