Results 71 to 80 of about 391,496 (277)
Attack Graph to Graph Database
IOSR Journal of Computer Engineering, 2014 Databases are an integral part of almost any computing system today, and users heavily rely on the services they provide. When we interact with a computing system, we expect that any data be stored for future use, that the data is able to be looked up quickly, and that we can perform complex queries against the data stored in the database.
openaire +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Join-Reachability Problems in Directed Graphs [PDF]
, 2010 For a given collection G of directed graphs we define the join-reachability graph of G, denoted by J(G), as the directed graph that, for any pair of vertices a and b, contains a path from a to b if and only if such a path exists in all graphs of G.
Georgiadis, Loukas +2 more
core
Statistical data mining for symbol associations in genomic databases
, 2013 A methodology is proposed to automatically detect significant symbol associations in genomic databases. A new statistical test is proposed to assess the significance of a group of symbols when found in several genesets of a given database.
Fournié, Jean-Jacques +2 more
core +3 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Using Graph Databases to Represent Knowledge Base in the Field of Cultural Heritage
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2016 This paper presents digital knowledge including context-based annotations of objects in the field of cultural heritage. Some major problems and solutions of digitalization of items, their processing, storing and organizing them in a repository are ...
Galina Bogdanova +2 more
doaj +1 more source
Relational database and graph database: A comparative analysis [PDF]
Journal of Process Management. New Technologies, 2017 Since 1970, relational database models have been in use for storing, manipulating and retrieving data. The importance of relational databases is going to decrease due to the exponential growth of data as it is difficult to work with large number of joining tables.
Surajit Medhi, Hemanta K. Baruah
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source