Results 91 to 100 of about 1,499,664 (294)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Informatics Solutions for Prosumers connected to Smart Grids [PDF]
Database Systems Journal, 2015 This paper gives a brief overview about electricity consumption optimization based on consumption profiles of electricity prosumers that are connected to smart grids.
Simona Vasilica OPREA
doaj
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
UMLtoGraphDB: Mapping Conceptual Schemas to Graph Databases [PDF]
, 2016 International audienceThe need to store and manipulate large volume of (unstructured) data has led to the development of several NoSQL databases for better scalability.
Cabot Sagrera, Jordi +6 more
core +1 more source
A Hierarchical Orthographic Similarity Measure for Interconnected Texts Represented by Graphs
Applied SciencesSimilarity measures play a pivotal role in automatic techniques designed to analyse large volumes of textual data. Conventional approaches, treating texts as paradigmatic examples of unstructured data, tend to overlook their structural nuances, leading ...
Maxime Deforche +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Diversified Top-k Graph Pattern Matching [PDF]
, 2013 Graph pattern matching has been widely used in e.g., social data analysis. A number of matching algorithms have been developed that, given a graph pattern Q and a graph G, compute the set M(Q;G) of matches of Q in G.
Wang, Xin +2 more
core
Query Languages for Graph Databases
, 2018 In the past few years many NoSQL databases have emerged, including graph databases. NoSQL databases have certain advantages and they can be used in certain domains as an alternative to relational databases.
Kornelije Rabuzin
core +1 more source