Results 101 to 110 of about 131,872 (295)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Diversified Top-k Graph Pattern Matching [PDF]
, 2013 Graph pattern matching has been widely used in e.g., social data analysis. A number of matching algorithms have been developed that, given a graph pattern Q and a graph G, compute the set M(Q;G) of matches of Q in G.
Wang, Xin +2 more
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Querying Encrypted Graph Databases [PDF]
, 2018 We present an approach to execution of queries on encrypted graph databases. The approach is inspired by CryptDB system for relational DBs (R. A. Popa et al).
Frans Coenen +5 more
core +1 more source
World Electric Vehicle JournalThis article introduces a novel hybrid database architecture that combines graph and time-series databases to enhance the storage and management of transportation data, particularly for electric vehicles (EVs).
Marko Šidlovský, Filip Ravas
doaj +1 more source
Using Graph Databases to Represent Knowledge Base in the Field of Cultural Heritage
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2016 This paper presents digital knowledge including context-based annotations of objects in the field of cultural heritage. Some major problems and solutions of digitalization of items, their processing, storing and organizing them in a repository are ...
Galina Bogdanova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Label Hierarchy in Graph Databases [PDF]
학위논문(석사) -- 서울대학교대학원 : 공과대학 컴퓨터공학부, 2024. 2. Bongki Moon.The popularity of graph databases can be explained by their ability to truthfully represent real-world data.
엠마 프뤼보스트
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Extracting fuzzy summaries from nosql graph databases [PDF]
, 2015 International audienceLinguistic summaries have been studied for many years and allow to sum up large volumes of data in a very intuitive manner. They have been studied over several types of data.
Anne Laurent +3 more
core +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source